ID   F9WLG9_TRYVY            Unreviewed;       412 AA.
AC   F9WLG9;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|Pfam:PF00078};
GN   ORFNames=TvY486_0010380 {ECO:0000313|EMBL:CCD18360.1};
OS   Trypanosoma vivax (strain Y486).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX   NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCD18360.1, ECO:0000313|Proteomes:UP000009027};
RN   [1] {ECO:0000313|EMBL:CCD18360.1, ECO:0000313|Proteomes:UP000009027}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Y486 {ECO:0000313|EMBL:CCD18360.1,
RC   ECO:0000313|Proteomes:UP000009027};
RX   PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA   Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA   Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA   Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA   Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA   Hertz-Fowler C., Berriman M.;
RT   "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT   African trypanosome species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR   EMBL; CAEX01000995; CCD18360.1; -; Genomic_DNA.
DR   AlphaFoldDB; F9WLG9; -.
DR   VEuPathDB; TriTrypDB:TvY486_0010380; -.
DR   OrthoDB; 119427at2759; -.
DR   Proteomes; UP000009027; Unassembled WGS sequence.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR36688; ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR36688:SF1; ENDO_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00078; RVT_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009027}.
FT   DOMAIN          82..259
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
SQ   SEQUENCE   412 AA;  45049 MW;  A553AB1FD286264B CRC64;
     MKKPRSSQCT FQPATEAEMD VALRELSSGT APGDDGIHFE EPKRLGRVSR RCILRLFKHS
     LCADHVPAKW RQGIVVPMLK PNEPASGMAS FRPVALTRTL CKRMERIVAR RVEDSIEDKL
     QPQRARFRPG QSTLDTLKQV TRHVRRRKDG EKTAVKFTDS ARPFDSVVRA CIVKGVLSFC
     VAKPQVAWTA GFPKGHAAKV RVNKVLSEKI GLTRGVPQVS ALGPVPFIVT VVSLSKRLDC
     IPVLQDGFFA DGRTMVSTSA DLSEIQRTIQ QGLGCSTRCS SECYVEVSAV ETGYKPFGAQ
     ATKLLSLKVG KAALKEGRAP KLLGLAVQPH ARAAKHVMRM KAAPGTRPLQ LSAVAAPERG
     PDREQLRAFC LALVQNKMCH GLAPWWFDTS LSDRERLEEG SGTGGAHSCG HS
//