ID G0HF04_CORVD Unreviewed; 298 AA.
AC G0HF04;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Ribosomal RNA methyltransferase {ECO:0000313|EMBL:AEK37216.1};
DE EC=2.1.1.187 {ECO:0000313|EMBL:AEK37216.1};
GN Name=rrmA {ECO:0000313|EMBL:AEK37216.1};
GN OrderedLocusNames=CVAR_1865 {ECO:0000313|EMBL:AEK37216.1};
OS Corynebacterium variabile (strain DSM 44702 / CIP 107183 / JCM 12073 /
OS NCIMB 30131) (Corynebacterium mooreparkense).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=858619 {ECO:0000313|EMBL:AEK37216.1, ECO:0000313|Proteomes:UP000006659};
RN [1] {ECO:0000313|EMBL:AEK37216.1, ECO:0000313|Proteomes:UP000006659}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44702 / JCM 12073 / NCIMB 30131
RC {ECO:0000313|Proteomes:UP000006659};
RX PubMed=22053731; DOI=10.1186/1471-2164-12-545;
RA Schroeder J., Maus I., Trost E., Tauch A.;
RT "Complete genome sequence of Corynebacterium variabile DSM 44702 isolated
RT from the surface of smear-ripened cheeses and insights into cheese ripening
RT and flavor generation.";
RL BMC Genomics 12:545-545(2011).
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DR EMBL; CP002917; AEK37216.1; -; Genomic_DNA.
DR RefSeq; WP_014010381.1; NC_015859.1.
DR AlphaFoldDB; G0HF04; -.
DR STRING; 858619.CVAR_1865; -.
DR KEGG; cva:CVAR_1865; -.
DR eggNOG; COG2226; Bacteria.
DR HOGENOM; CLU_050931_1_0_11; -.
DR Proteomes; UP000006659; Chromosome.
DR GO; GO:0052911; F:23S rRNA (guanine(745)-N(1))-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR016718; rRNA_m1G-MeTrfase_A_prd.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF13649; Methyltransf_25; 1.
DR PIRSF; PIRSF018249; MyrA_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR018249-1};
KW Methyltransferase {ECO:0000313|EMBL:AEK37216.1};
KW S-adenosyl-L-methionine {ECO:0000256|PIRSR:PIRSR018249-2};
KW Transferase {ECO:0000313|EMBL:AEK37216.1};
KW Zinc {ECO:0000256|PIRSR:PIRSR018249-1}.
FT DOMAIN 102..186
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 74
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 109..110
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 197
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
SQ SEQUENCE 298 AA; 31581 MW; 3D28CC41615FF5C7 CRC64;
MLSDVIDLLA DPVDGTPLRA GDESWRTIVS GSGHSYDVAR RGYVTLVGGA GLRYTGDDAD
MITAREAFLA GGHFAPFVEA VSDAVADVLD DNHVSENDRP SVVEIGAGTG YYLAHTLDAV
PGSRGIGIDV SVPAAKRLAH CHPRVGAVIA DAWARLPLRD DSIDAVTVIF APRNAAEFAR
VLTPEGQVVV LTPDVGHLGE LRAPLGIIDV EEGKVERMIT QASGYLVPVG EPEHVEFVMH
LDQASIAAQI GMSPSARHIH PKVLAERIAD LPPVMEVTAR ATVTRLARDP RTLGFNGS
//
