ID G0HMS0_THES4 Unreviewed; 478 AA.
AC G0HMS0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Proline dehydrogenase, alpha subunit {ECO:0000313|EMBL:AEK73652.1};
GN OrderedLocusNames=GQS_08790 {ECO:0000313|EMBL:AEK73652.1};
OS Thermococcus sp. (strain CGMCC 1.5172 / 4557).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=1042877 {ECO:0000313|EMBL:AEK73652.1, ECO:0000313|Proteomes:UP000000874};
RN [1] {ECO:0000313|EMBL:AEK73652.1, ECO:0000313|Proteomes:UP000000874}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.5172 / 4557 {ECO:0000313|Proteomes:UP000000874};
RX PubMed=21914870; DOI=10.1128/JB.05851-11;
RA Wang X., Gao Z., Xu X., Ruan L.;
RT "Complete genome sequence of Thermococcus sp. strain 4557, a
RT hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent
RT area.";
RL J. Bacteriol. 193:5544-5545(2011).
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DR EMBL; CP002920; AEK73652.1; -; Genomic_DNA.
DR RefSeq; WP_014013334.1; NC_015865.1.
DR AlphaFoldDB; G0HMS0; -.
DR STRING; 1042877.GQS_08790; -.
DR GeneID; 11016439; -.
DR KEGG; the:GQS_08790; -.
DR PATRIC; fig|1042877.9.peg.1712; -.
DR eggNOG; arCOG01294; Archaea.
DR HOGENOM; CLU_030705_2_0_2; -.
DR OrthoDB; 27922at2157; -.
DR Proteomes; UP000000874; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR PANTHER; PTHR42949; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B; 1.
DR PANTHER; PTHR42949:SF2; ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 15..97
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 478 AA; 52120 MW; A7D10233F35CF9D8 CRC64;
MRLTEHPVLR FERGREVTIY FEGRPIKAYE GETIATALHA AGVRVLNYSA NEKRPRGLFC
AIGKCSSCLM VVNGIPNVRS CITLVEDGMR IEPQRGKAKL PKEAKPPEFK DAKVVRADVV
VVGGGPAGLM AAIHAADAGA SVILIDEQPM LGGQLVKQTH KFFGKREQFA GVRGVEIAKI
LEDEARKREN VEIFLETSAV GIFQEGDEKL VLAVKNNREL IEFRGRAVIV ATGAMEKMIP
FENNDLPGIY GAGAIQTLMN TYGVKPGDRV LIVGAGNVGL ILAYQLIQAG VEVKAIVEAM
PKVGGYFVHA AKVRRLGVPI LTRHTILRAE GKEKVERAVV AQLDENWRVI PGTERTFEVD
VIALAVGLRP SIELLHQAGC QIRYVRELSG HVAVRDEWME TTVRGIFVAG DSAGIEEATT
AMLEGKVAGI AAALRLGIAD ESWLKEMEKA QKDLLEFRSG PFGRHVLEGI KKALVVRE
//
