ID G0LMQ9_HALWC Unreviewed; 621 AA.
AC G0LMQ9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Kef-type transport system {ECO:0000313|EMBL:CCC41379.1};
GN Name=kef1 {ECO:0000313|EMBL:CCC41379.1};
GN OrderedLocusNames=Hqrw_3635 {ECO:0000313|EMBL:CCC41379.1};
OS Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloquadratum.
OX NCBI_TaxID=768065 {ECO:0000313|EMBL:CCC41379.1, ECO:0000313|Proteomes:UP000007954};
RN [1] {ECO:0000313|EMBL:CCC41379.1, ECO:0000313|Proteomes:UP000007954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16854 / JCM 12705 / C23
RC {ECO:0000313|Proteomes:UP000007954};
RX PubMed=21701686; DOI=10.1371/journal.pone.0020968;
RA Dyall-Smith M., Pfeiffer F., Klee K., Palm P., Gross K., Schuster S.C.,
RA Rampp M., Oesterhelt D.;
RT "Haloquadratum walsbyi: limited diversity in a global pond.";
RL PLoS ONE 6:E20968-E20968(2011).
CC -!- FUNCTION: Part of a potassium transport system.
CC {ECO:0000256|ARBA:ARBA00003660}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FR746099; CCC41379.1; -; Genomic_DNA.
DR RefSeq; WP_011572309.1; NC_017459.1.
DR AlphaFoldDB; G0LMQ9; -.
DR GeneID; 4194172; -.
DR KEGG; hwc:Hqrw_3635; -.
DR HOGENOM; CLU_005912_10_1_2; -.
DR OrthoDB; 11709at2157; -.
DR Proteomes; UP000007954; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR PANTHER; PTHR32507:SF0; NA(+)_H(+) ANTIPORTER 2-RELATED; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 404..517
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 537..619
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 621 AA; 65014 MW; E3433C56C1DE56DB CRC64;
MAGAGGNLIA VVAAIIGIGV IAQILSDRFQ VPSVVFLITA GIILGPEVLG VVGPDSFGSA
LSAIVGLSVA IIVFEGAFHL RIQKLREAPT ATLKLVTIGA GIALIGTAIT VRFLLSTSWN
VAFLVGALLV ATGPTVVTPI LEVVPVRDRV EAALETEGIV NDVTAAILAI VIFEAITAGV
TQPGALLQLF TERLGIGLLI GAIVATLLVY GLQYIDLSPG NAPQNARLLV LAGALVAYGA
ADFIATEAGI AAVATAGIIL GNIDIPYEEE ISAFKGDITL IVLSFVFIAL AALLEFEILR
MIGLPGLGIT AIVALVLRPL LVFISTRGDR FTSGEQLFMS FVGPRGIIPA SVATLFAIEL
RNAGMDQAAN ILVGTVFLVI LITVVAEGGF ARQIAEYLDI IPMRVLVVGG GTVGRALADR
LENRGENVVL IEQSQEVVEV GRNEGLAVHH GDGTDTDVLA SAGGDNARIV VGATGDDDVN
LLVSQLARSK FDPETILARV NNPDNAEAFE DLGVRNISTS IATAQALDNY IERPAMMDWM
GEIGYSGDIQ EIEVTSEDLI GRPIRDIGPE LPPDSLIALI KRDGNIRVPE ADLTLEHGDQ
VTVIGGRDEV KDAIKFIHPD K
//
