ID G0MN12_CAEBE Unreviewed; 413 AA.
AC G0MN12;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Pseudouridine synthase I TruA alpha/beta domain-containing protein {ECO:0000259|Pfam:PF01416};
GN ORFNames=CAEBREN_00927 {ECO:0000313|EMBL:EGT38269.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; GL379803; EGT38269.1; -; Genomic_DNA.
DR AlphaFoldDB; G0MN12; -.
DR STRING; 135651.G0MN12; -.
DR EnsemblMetazoa; CBN00927.1; CBN00927.1; WBGene00139652.
DR eggNOG; KOG2554; Eukaryota.
DR HOGENOM; CLU_014673_2_0_1; -.
DR InParanoid; G0MN12; -.
DR OMA; DCKFPEM; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02569; PseudoU_synth_ScPus3; 1.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR041707; Pus3-like.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 196..311
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 413 AA; 47790 MW; 86DF8CD9ABD37C78 CRC64;
MSFPCKKQLF AKKAEKRQSP DDQNQQKAKK PKILDFSAHP KRKIAFQFYY LGWEHDGLVQ
QLDTANTVEK HLMDALLKTK MIESWENCEF SRCGRTDKGV SAFKQTAAVV VRSTCPQDPD
VFWDESTPED VKNNYKSKPE ELPYVKMLNG LLPKTIRVFA WAPVKREFNA RFDCNRRTYK
YSFAKADLDL EKMREAASLL IGEHDYINFC QMDLNEKRLT QATVRKIYEV KVEQVSTHPG
NDIYSMVELT VSGSGFLWHM IRYIVTVLQE IGRGNEQPTL VSELLDTQKY PGRPHYTLSS
DTPLCLFDCG YKEEDVAWIY DSDIKKTIVG LQKTWAAYQA RSRMMENMLE ELTGMVEMAP
GEVTKGLHEF VQDRPIQMKY VKFEQREMCD TVELKKQKLA MKIAEKSEAV GGK
//
