ID   G0N2T4_CAEBE            Unreviewed;       309 AA.
AC   G0N2T4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Pre-mRNA-splicing factor SPF27 {ECO:0000256|ARBA:ARBA00014158};
GN   ORFNames=CAEBREN_18269 {ECO:0000313|EMBL:EGT50981.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the SPF27 family.
CC       {ECO:0000256|ARBA:ARBA00010788}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL379831; EGT50981.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0N2T4; -.
DR   STRING; 135651.G0N2T4; -.
DR   EnsemblMetazoa; CBN18269.1; CBN18269.1; WBGene00156994.
DR   eggNOG; KOG2520; Eukaryota.
DR   eggNOG; KOG3096; Eukaryota.
DR   HOGENOM; CLU_900880_0_0_1; -.
DR   InParanoid; G0N2T4; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR008409; SPF27.
DR   InterPro; IPR006086; XPG-I_dom.
DR   PANTHER; PTHR13296; BCAS2 PROTEIN; 1.
DR   PANTHER; PTHR13296:SF0; PRE-MRNA-SPLICING FACTOR SPF27; 1.
DR   Pfam; PF05700; BCAS2; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068}.
FT   DOMAIN          123..198
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          280..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          213..240
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   309 AA;  35840 MW;  8CE6A56EB54BD279 CRC64;
     MQSFDIFSVF GRFKVQKAMK NPKMSSRPGK LSKILKFTPF LDDSSDGHIG LYKSLKGCQA
     HHQHIENSYL IPFFSNFLQH KITPIVVFDT CNAKDGDQEE FVAGKKRGSW NLPGPNATRK
     SRIFAPGDGE AQCAQLEASG ETSKCITTDF DYFLFGGKDL YLFDFTVPVD TLPYLDTEYN
     EEDRQNAMKH SKAQNEHLLF RQINLELMDE YATESYLQRN KQMETLLTEV EKELRNTKEA
     VMEVHASRKR EQMKAGEKVK QLNHSWVQMV TNNYKMEIEN RQMERDNAKQ VKRLKLDPAK
     LEEKEDQEN
//