ID G0NRH7_CAEBE Unreviewed; 655 AA.
AC G0NRH7;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=CBN-TWK-39 protein {ECO:0000313|EMBL:EGT36206.1};
GN Name=Cbn-twk-39 {ECO:0000313|EMBL:EGT36206.1};
GN ORFNames=CAEBREN_15495 {ECO:0000313|EMBL:EGT36206.1};
OS Caenorhabditis brenneri (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN [1] {ECO:0000313|Proteomes:UP000008068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA Wilson R.K.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR EMBL; GL379932; EGT36206.1; -; Genomic_DNA.
DR AlphaFoldDB; G0NRH7; -.
DR STRING; 135651.G0NRH7; -.
DR EnsemblMetazoa; CBN15495.1; CBN15495.1; WBGene00154220.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_022504_5_4_1; -.
DR InParanoid; G0NRH7; -.
DR OMA; KNESQWA; -.
DR Proteomes; UP000008068; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 556..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..176
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 503..579
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 223..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..622
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 75434 MW; 7AF6F1C7F8D4D7C0 CRC64;
MRDEVRSFCL KVTTFVRTAT IFTITHVGLC FLVALYAVAG AFMFQAVEYP YELGLQGKVK
NASLKVVGDI YRFINKKSVI EETAVKNESQ WALKEFEMLL VHAMNFEGYD EHDEERPTFQ
WTFSGALLYS ITVFTTIGYG HICPKTDTGR LLTILYSVLG IPLMLLCLAN IAETLAQVFT
YIYFKLCCAY CRWQKNRRRV RRAALSFRYH PNAAVNVRRV QSSRSNQRYN TVRRHASLNR
SRTRSNDTKS VRSFNRYEST NTQPTQPARF DTMSLPGRRK ISTQSRSPNG TMPRLPNFPQ
AKRSFRGGAH LQKSNTAINM EQLYTDEKRS RRGRHAVSES PAREYKGGLL VRAQHQPDEG
VVDLKAYGGS AAAFHDLVTR KQRRDDAVPN VIISRTRDED VKSDPEKTEE TSMSLTDDED
MQKPPRRNNS ARELREKEMM MMHSMTHKQP SMDSSTSRRM RDIDGRSYRS DRSERSDEMS
LHSLRRNGHR NHEKMPVSVG ICIVFAFISG GAWLFAWWEN WNGFDGAYYC FITLSTIGFG
DIVPGQALDE GSQEKLVVCA LYLLFGMALI AMCFKLMQDD VVQKARWLGQ KIGILVRDES
SESESDFDDD MIEEDEEDMS EERNDQVYDK RTISSGSSKQ NDEYIHPRKY HHHRR
//
