ID   G0PGY9_CAEBE            Unreviewed;       630 AA.
AC   G0PGY9;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350, ECO:0000256|PIRNR:PIRNR038922};
GN   ORFNames=CAEBREN_03357 {ECO:0000313|EMBL:EGT55866.1};
OS   Caenorhabditis brenneri (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=135651 {ECO:0000313|Proteomes:UP000008068};
RN   [1] {ECO:0000313|Proteomes:UP000008068}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PB2801 {ECO:0000313|Proteomes:UP000008068};
RG   Caenorhabditis brenneri Sequencing and Analysis Consortium;
RA   Wilson R.K.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER).
CC       {ECO:0000256|PIRNR:PIRNR038922}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC       ECO:0000256|PIRNR:PIRNR038922}. Endoplasmic reticulum
CC       {ECO:0000256|ARBA:ARBA00004240}.
CC   -!- SIMILARITY: Belongs to the SRP72 family.
CC       {ECO:0000256|ARBA:ARBA00007676, ECO:0000256|PIRNR:PIRNR038922}.
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DR   EMBL; GL380452; EGT55866.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0PGY9; -.
DR   STRING; 135651.G0PGY9; -.
DR   EnsemblMetazoa; CBN03357.1; CBN03357.1; WBGene00142082.
DR   eggNOG; KOG2376; Eukaryota.
DR   HOGENOM; CLU_013808_1_0_1; -.
DR   InParanoid; G0PGY9; -.
DR   OMA; ELACNER; -.
DR   Proteomes; UP000008068; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR   InterPro; IPR026270; SRP72.
DR   InterPro; IPR031545; SRP72_TPR-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR   PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR   Pfam; PF08492; SRP72; 1.
DR   Pfam; PF17004; SRP_TPR_like; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   PIRSF; PIRSF038922; SRP72; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038922};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008068};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|PIRNR:PIRNR038922};
KW   Signal recognition particle {ECO:0000256|ARBA:ARBA00023135,
KW   ECO:0000256|PIRNR:PIRNR038922}.
FT   DOMAIN          511..568
FT                   /note="Signal recognition particle SRP72 subunit RNA-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF08492"
FT   REGION          538..630
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..597
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  70780 MW;  85CFCB28D838491D CRC64;
     MADPSAGGLY QCLNDISRAD TSGDYQKALQ AANKLIRKHP KETYAFKCKL VAQIQLSQWA
     DALELIRKTP SHQMGRVGFE TAYIHYRQGN LDEAINSLNT CDADDVKAKE LKAQIFYKQE
     KFEEAFDIYL DLIKNYSDDN DDLRRTNFLA VQARLEAQGK KQQVDQLEDS YSQHYNKACV
     DIEAERLKQA SESLDKALVF CEKSIEDEEE MEEELDTIRV QKAYVLQRQG NKKEALEIYQ
     KVQAANPSDE SVKATIINNI PAASSDFALA DSRKRFKAAL QIDQSKLTRR QRRTLMLNNA
     LVLLMSNQRE PCKRALEELV SKFGTSKEVA LIEASLHVKL GDTESALKVL EGSDLEQSVA
     RLHVLLNANR LPEAIKAIKS LSISSELGPS SLLTSTLIAA DSKDEAVKAL ASASTAKNQS
     PEAVKAILEA LVEAEQSRGN DKDATKHLEK LVEKFPDDLQ LQCRLVGAYS KTDSKKADAL
     SAKLFPESME VDVNVDELEE SDWILYGEKY RQKKEAKSPA VPDSGIITRK LKNVNRKRKI
     RLPKNYNPAV APDPERWLPR QERSTYKKKR KNREREIGRG TQGSSSANPN VEFVSASPNS
     PRPLPGPVAE GPRQQRPNFQ KQKKKKASKF
//