ID G0RZ56_CHATD Unreviewed; 552 AA.
AC G0RZ56;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Dihydrosphingosine 1-phosphate phosphatase-like protein {ECO:0000313|EMBL:EGS23484.1};
GN ORFNames=CTHT_0001770 {ECO:0000313|EMBL:EGS23484.1};
OS Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
OS (Thermochaetoides thermophila).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Thermochaetoides.
OX NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN [1] {ECO:0000313|EMBL:EGS23484.1, ECO:0000313|Proteomes:UP000008066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC {ECO:0000313|Proteomes:UP000008066};
RX PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA Arumugam M., Bork P., Hurt E.;
RT "Insight into structure and assembly of the nuclear pore complex by
RT utilizing the genome of a eukaryotic thermophile.";
RL Cell 146:277-289(2011).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the type 2 lipid phosphate phosphatase family.
CC {ECO:0000256|ARBA:ARBA00038324}.
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DR EMBL; GL988032; EGS23484.1; -; Genomic_DNA.
DR RefSeq; XP_006690726.1; XM_006690663.1.
DR AlphaFoldDB; G0RZ56; -.
DR STRING; 759272.G0RZ56; -.
DR GeneID; 18254215; -.
DR KEGG; cthr:CTHT_0001770; -.
DR eggNOG; KOG2822; Eukaryota.
DR HOGENOM; CLU_019266_0_0_1; -.
DR OMA; ADDCPCY; -.
DR OrthoDB; 2958177at2759; -.
DR Proteomes; UP000008066; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03388; PAP2_SPPase1; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR PANTHER; PTHR14969:SF28; DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED; 1.
DR PANTHER; PTHR14969; SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE; 1.
DR Pfam; PF01569; PAP2; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008066};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 110..230
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 552 AA; 61412 MW; 6CE203F32A14F660 CRC64;
MSTATTNGAS NGAAPKDEPV EKKEPNGTVD AGLKSLEHYK RALPRWRYRL RQRLLPIVRW
ETPHLARLQR ALRTPALDYY FAWTANLGTH TFFMIMLPVL FWCGEPAYGK GIVHILATGV
FFTGFIKDMF SLPRPLSPPL HRITMSGSAA LEYGFPSTHS ANAVSVAVYS LLKLREHSAA
FSPSTALALE VLAYFYAVSI VFGRLYCGMH GFLDVITGSA LGALISLIEF HCAPWIEEWL
QSSSYLAPLT IVLFILLFVR IHPEPADDCP CFDDSVSFAG VMIGLELGTW RFARYSPLAP
VYVGTNPTFD LSALTWPVAL GRIVLGIAVI VSWREVMKPT LLKLLPHLYR VFETYGLSLP
RKFFTPASKY KDVPLRGLKD DNVLPHVADV AKAVKSIRGP GRGRAVSVGP QSAADAYETL
AWRERKRRES LSRERNALKS KKSVGGLQKG EQQVECRQVS GVRSGGRKEE FEQGEVVEVV
SEGELELEEE EELLDEKDVF SRVVKPRVRY DVEVVTKLVV YAGIGWLSVD PILILFELIG
LGTGQYPGLN LR
//
