ID G0S3W8_CHATD Unreviewed; 765 AA.
AC G0S3W8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 03-MAY-2023, entry version 40.
DE SubName: Full=Ubiquitin-protein ligase-like protein {ECO:0000313|EMBL:EGS22030.1};
GN ORFNames=CTHT_0039150 {ECO:0000313|EMBL:EGS22030.1};
OS Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
OS (Thermochaetoides thermophila).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Thermochaetoides.
OX NCBI_TaxID=759272 {ECO:0000313|Proteomes:UP000008066};
RN [1] {ECO:0000313|EMBL:EGS22030.1, ECO:0000313|Proteomes:UP000008066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1495 / CBS 144.50 / IMI 039719
RC {ECO:0000313|Proteomes:UP000008066};
RX PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA Arumugam M., Bork P., Hurt E.;
RT "Insight into structure and assembly of the nuclear pore complex by
RT utilizing the genome of a eukaryotic thermophile.";
RL Cell 146:277-289(2011).
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; GL988041; EGS22030.1; -; Genomic_DNA.
DR RefSeq; XP_006694326.1; XM_006694263.1.
DR AlphaFoldDB; G0S3W8; -.
DR STRING; 759272.G0S3W8; -.
DR GeneID; 18257953; -.
DR KEGG; cthr:CTHT_0039150; -.
DR eggNOG; KOG2166; Eukaryota.
DR HOGENOM; CLU_004747_6_1_1; -.
DR OMA; IREWDRY; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000008066; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EGS22030.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008066}.
FT DOMAIN 409..640
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 765 AA; 87974 MW; 2774F68147FA065A CRC64;
MPPPMSGLPS RPMDDIDSTW AYLQQGITRI MMNLQEGLDL QTYMGIYTAV HNFCTSQKAA
GFTLTTAAVG AAQRGAHLVG EDLYRKLSDY LTEHLTALVQ QSKTHTDEAL LQFYIREWQR
YTDAAKYIHH LFRYLNRHWV KREMDEGKKN VYDVYTLHLV RWRDVLFAQV SEKVMDAVLK
LVERQRLGET IEHSQIKAVV DSFVSLGLDE GDSSKTTLEV YRYHFERPFL EATRQFYQKE
SKQFVAENSV VEYMKKAEAR LREEEERVKL YLHPDIAIPL KKACNEVLIA DHQNLLREEF
QVLLDNDREE DMARMYNLLS RISDGLDPLR AKFETHVRNA GLAAVAKVAS DAEKLEPKTY
VDALLEVHTQ YSGLVKRAFN DEPEFTRSLD NACREFVNRN EVCKAGSNKS PELLAKYTDV
LLRKSGTGVE DAELESTLAQ VMTVFKYIED KDVFQKFYSR MLARRLVHSN SSSDDAEMSM
ISKLKEACGF EYTNKLQRMF QDMQISKDLN NGYKEHLSAV GVKGLDSTFS ILGTGFWPLT
PPNTSFNPPE EVNADCERFA RFYKNKHEGR KLTWLWQLCK GEVKTNYIRN AKMPYIFQVS
AYQMAILLLF NEKDRNTYEE IASSTALNAE ALDPSLGILL KAKVLLLEGG GGKVGPGAVF
ALNYDFKNKK FRVNLNVGMK SETKQEEAET NKTIEEDRKL LLQSAIVRIM KARKRMKHQQ
LVSETINQIK SRFMPKVADI KKCIEILLDK EYLERLDDDD IGYLA
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