ID G0TXT6_TRYVY Unreviewed; 259 AA.
AC G0TXT6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=TVY486_0701180 {ECO:0000313|EMBL:CCC48778.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC48778.1};
RN [1] {ECO:0000313|EMBL:CCC48778.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC48778.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR EMBL; HE573023; CCC48778.1; -; Genomic_DNA.
DR AlphaFoldDB; G0TXT6; -.
DR VEuPathDB; TriTrypDB:TvY486_0701180; -.
DR OrthoDB; 132303at2759; -.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR15481:SF0; LD23870P-RELATED; 1.
DR PANTHER; PTHR15481; RIBONUCLEIC ACID BINDING PROTEIN S1; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 5..84
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 86..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..226
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 259 AA; 30086 MW; 2F14DEE7531A82DE CRC64;
MTTNVIARIT NLPANVTEAH LHELIEPFAK IEKVKMPTPT LWLTCPTGRA EVHGATIEDT
KLVYVHLHGT VIDGNRINVS FAKISSNGKE SSPRLPERRD RVSRRSRSSS NERRRGRGSR
RSRSSSGERR RDRESRRSRS SSNERRRGRG SRRSRSSSGE RRRDRESRRS RSSSNERRRG
RGSRRSRSSS GERRRERRRR RYSDDRRSKK REKRRSRRRS ASRKRRRYSS SSTESYSSQD
YSSSASRSSA SSSSGSWSD
//
