ID G0U1R5_TRYVY Unreviewed; 623 AA.
AC G0U1R5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Putative sec1 family transport protein {ECO:0000313|EMBL:CCC50214.1};
GN ORFNames=TVY486_0900370 {ECO:0000313|EMBL:CCC50214.1};
OS Trypanosoma vivax (strain Y486).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Duttonella.
OX NCBI_TaxID=1055687 {ECO:0000313|EMBL:CCC50214.1};
RN [1] {ECO:0000313|EMBL:CCC50214.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Y486 {ECO:0000313|EMBL:CCC50214.1};
RX PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA Hertz-Fowler C., Berriman M.;
RT "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT African trypanosome species.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
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DR EMBL; HE573025; CCC50214.1; -; Genomic_DNA.
DR AlphaFoldDB; G0U1R5; -.
DR VEuPathDB; TriTrypDB:TvY486_0900370; -.
DR OrthoDB; 1122949at2759; -.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.60; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679:SF2; SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR PIRSF; PIRSF005715; VPS45_Sec1; 2.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 3: Inferred from homology;
SQ SEQUENCE 623 AA; 68335 MW; 6833542211602FDA CRC64;
MLDQKKHFLR QRQKDVISAM ISSAYPLGPG GVPQSPLPAS SDQATAVTWR LLVYDDVGRS
IIAPLLRVGD LRELGVTLYM HIKQKRDPVP GAPVVYFCAP TEENTDIIAS DAINELYEWM
YVNFTAQVTR HGLELFAEKL TRGELQSIQH IKVFDRTLNY ISLEDDLFVL MQKNSFITLN
SRHVKEEEVD AHLGEIVLGI SHILISQQVL PVIVHSRTGA AEEVAKRLSV CLNDHLTDRT
LTPAASNALG RPLLLIVDRT SDLATLLHHP FSYRGLLVDV GNMHLNKVSV VGEDGKTNSF
EIDPDRDGFY RANSFLDFSA VGDNINMAVK KYGEEYAALS GTSCSTEEAD ASSVSMLLAN
APKLSEEKRM LDAHTKMAYC LLHHIRQNQL DRFHGVELGL LRREEADHEE LAKLLLSKSG
TLEDRQRLYL LAYLTDTQGA HEALLQQCLS AFGGSPFPAL TYVKRLRSWC PGAATPSGVE
PGAAQGFTWG LAQTLAKNIV NSLGSNAKSE LPLTKLVDAL MQDSSAASGA STGRSAGASN
LRTELLGTVV GYDPRTKKAV NINEMHFSQA IVFNIGGGCV AEYEDLKRWE ASHPRKAVSY
GCTSLLTGNE ALQQLTVLGQ DLP
//
