ID   G0V343_TRYCI            Unreviewed;      1716 AA.
AC   G0V343;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Uncharacterized protein TCIL3000_11_15760 {ECO:0000313|EMBL:CCC96066.1};
GN   ORFNames=TCIL3000_11_15760 {ECO:0000313|EMBL:CCC96066.1};
OS   Trypanosoma congolense (strain IL3000).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX   NCBI_TaxID=1068625 {ECO:0000313|EMBL:CCC96066.1};
RN   [1] {ECO:0000313|EMBL:CCC96066.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=IL3000 {ECO:0000313|EMBL:CCC96066.1};
RX   PubMed=22331916; DOI=10.1073/pnas.1117313109;
RA   Jackson A.P., Berry A., Aslett M., Allison H.C., Burton P.,
RA   Vavrova-Anderson J., Brown R., Browne H., Corton N., Hauser H., Gamble J.,
RA   Gilderthorp R., Marcello L., McQuillan J., Otto T.D., Quail M.A.,
RA   Sanders M.J., van Tonder A., Ginger M.L., Field M.C., Barry J.D.,
RA   Hertz-Fowler C., Berriman M.;
RT   "Antigenic diversity is generated by distinct evolutionary mechanisms in
RT   African trypanosome species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:3416-3421(2012).
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DR   EMBL; HE575324; CCC96066.1; -; Genomic_DNA.
DR   VEuPathDB; TriTrypDB:TcIL3000.11.15760; -.
DR   OrthoDB; 7433at2759; -.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR   CDD; cd18091; SpoU-like_TRM3-like; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR045330; Trm3/TARBP1.
DR   InterPro; IPR044748; Trm3/TARBP1_C.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR12029:SF11; METHYLTRANSFERASE TARBP1-RELATED; 1.
DR   PANTHER; PTHR12029; RNA METHYLTRANSFERASE; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
PE   4: Predicted;
FT   DOMAIN          1559..1701
FT                   /note="tRNA/rRNA methyltransferase SpoU type"
FT                   /evidence="ECO:0000259|Pfam:PF00588"
SQ   SEQUENCE   1716 AA;  192249 MW;  8B1F0114D8F54C47 CRC64;
     MDAKIEDLLL ALLRRFAERN IEVHPSLAFD VARDLVNAMC VAERRLQLAR IITLLQSGEG
     KHVESLVSCS GALMISQCDG KWWTSTEDAV HWEELMMSIL AAHPPFTRRV LASVSYCVVR
     VTLAGRGDMI LRSVGGSLCG TAAGHHIPRD VSIEVLPYFA DALVALHQGG AGEVKKASGE
     TTGAACEIVC GPEVMKRVIS YALDAIPCLS ADAAQATYLS RRVLVPLLLL GDGPSMDGIR
     SRIPLLLNSL SSDKPKRMEA IVITAALFEY LFRCRNGSRV DDYRCSASLW DTIHMVLKNA
     YSSNESEESR VNMQLRVEYL LKRIVSITHE QEKEEKWCNA VVYHPLFVWM PGISNNLWEM
     FFLVLEVTND YGMHIIQPAL PKLDALMDKV ALDTVVWDKF NRTGEEAELK QLVAGFHPMW
     VEILMMKMLT HPNVAFRKIG LMKLWSQAPS LLKLFSNTFL FTNAMDISLD TRLCAEVDRT
     PHLLSFFGPN SFEGAEVSVA GVAGPLGDQL GQFYATLFTH VVRDPGGRRE AMWRMLHCVA
     EKPNIHGATM LFRILHDVAE ALVGEECEKG REGTTEMITN GDVLREFMLV LRDAAQEKVP
     FWIDVRLSAI AFHILLQFAR INTERVRGCA DFWRVLCMCG PLGTSAGNSA TSVDSIAQVG
     TVGTCLDPRF LNEHLFTTSC KVQCGGTNYG FMRVMLQADV LVENVRSFLR SHQFDETHGK
     QLMFLVGALD RGDECDKGLL STVALELTET LLSIGRRPYN SVDSTLASLI LFVEFHHSLG
     SQTCSRYFSF NNISEISNTI NEFAVSSIRR ALHSIKVVTK LEDFSEEAWL LQGTLRWDTV
     VAAIVSVTQI ASCYHMSTRA LTLKTDQYLT EFIGLLGDVS KMSLGSTAGV QSQGMVQRFA
     QIVVSRNASR VVKGILCGVA EVDATVELDA QSKRGEESLL HCTVEDRLPT WIRALMDCPA
     LRLTTCDIPC SLTDLSWSTV LAQYYGSVYD SIFLLCNCVN LGAVPSLVQE IQEYGMDHVE
     RCWGSNLTSV YTILSWVAAI TNHFTDSEDS VDIDISGIIN SMFSHLNDVG GREHCRMAVL
     AYDTLRYGLE TEEELVKSHI RGALMDDSQS DRTSYVAAVM LSAEVLRNPA ANWPRLKELL
     LHVAVLHNPS REEEMFEVLV SAMEPLIVAE WPQTMREQYP PTVQLSLVGR SMAISAILWC
     CREKEEWARD VSLTLLEWSC SHTEVSHEPC MPNSKPHRSR MRLWQLLCSL VPMIDDPTLQ
     RDLLQKVVTK CLTLTNMGSV RRLIELYALQ LLQKQPELYP VVDGAMADYT LRPQVLGSYV
     FLCAHVILQE LRGEVKKVDG LMEKLLYRLF QQSTSHQHLL RLVCHIGLNL IHEACNSKGI
     KFSANEERML DYISNAPEHV KFRVQHVQQL FFDIREASTP RWLFCTQRKE GNNILAVSLP
     AAAFERMRFV GRELTCLTGA QNSVDMLRIK SVIRRLDTHR LLEPFEEFPY IPHTERSALY
     CPDYTHDALA LLVADPHDTA VSRAVSCSEN IQRKATPWWS TQLYNELHPR VLKAERQSVI
     VVASLLQNPV NVAGLFRCGE VFAVERVVVS EPSVLEHPHF VAAARSANLW LPWTAVQTRM
     LSAYLLSMRQ HGYALVGIEQ TAGSVSIETY QFPKKCVIVL GAEGHGIPAH LLPLLDICVE
     IPQYGLIRSL NVHVTGSIVI YEYTRQHRLQ SSTVNS
//