ID G0V5X9_NAUCC Unreviewed; 343 AA.
AC G0V5X9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN Name=NCAS0A03090 {ECO:0000313|EMBL:CCC66867.1};
GN OrderedLocusNames=NCAS_0A03090 {ECO:0000313|EMBL:CCC66867.1};
OS Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC
OS 1992 / NRRL Y-12630) (Yeast) (Saccharomyces castellii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX NCBI_TaxID=1064592 {ECO:0000313|EMBL:CCC66867.1, ECO:0000313|Proteomes:UP000001640};
RN [1] {ECO:0000313|EMBL:CCC66867.1, ECO:0000313|Proteomes:UP000001640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630
RC {ECO:0000313|Proteomes:UP000001640};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Type strain:CBS 4309;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Naumovozyma castellii.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; HE576752; CCC66867.1; -; Genomic_DNA.
DR RefSeq; XP_003673258.1; XM_003673210.1.
DR AlphaFoldDB; G0V5X9; -.
DR STRING; 1064592.G0V5X9; -.
DR GeneID; 11526911; -.
DR KEGG; ncs:NCAS_0A03090; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_9_2_1; -.
DR InParanoid; G0V5X9; -.
DR OMA; RAYMLAK; -.
DR OrthoDB; 1200131at2759; -.
DR Proteomes; UP000001640; Chromosome 1.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR PANTHER; PTHR10366:SF853; NADPH-DEPENDENT ALDEHYDE REDUCTASE ARI1-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001640}.
FT DOMAIN 3..257
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 343 AA; 38717 MW; 6779BF25B61C4459 CRC64;
MSVFISGATG FVAQHIINQL LEQNFKVIGS VRSQAKADKL LRQFNSNKNL SLEVVEDISN
LAAFDEVFSK HGKEIKYVLH TSSPFFTECD DYEKDLLIPA LNGTKGILNS ILKYAADNVE
RVVITSSIAA MFDFTRDLDP SYFYDENSWN PDSYQEALTD GGHAYNGSKK FAERYAWNFV
QEHKNEIKFK LTTVNPCYVF GPQLFDENVT AKLNTSCELI NKLLHLSAGD AVDNFFVGNF
VDVRDVAKAH LLGFENQNLV DKRLLLISSR FNAQDILDIM NEDFKTLEGQ LPAGVPHTGA
LHQWKGAIAD NSKTKELLGF EFIPLKKTID DMVTQILRKE KRL
//
