ID   G0WAW4_NAUDC            Unreviewed;      1287 AA.
AC   G0WAW4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   Name=NDAI0E00680 {ECO:0000313|EMBL:CCD24884.1};
GN   OrderedLocusNames=NDAI_0E00680 {ECO:0000313|EMBL:CCD24884.1};
OS   Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC
OS   0211 / NRRL Y-12639) (Saccharomyces dairenensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Naumovozyma.
OX   NCBI_TaxID=1071378 {ECO:0000313|EMBL:CCD24884.1, ECO:0000313|Proteomes:UP000000689};
RN   [1] {ECO:0000313|EMBL:CCD24884.1, ECO:0000313|Proteomes:UP000000689}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639
RC   {ECO:0000313|Proteomes:UP000000689};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR   EMBL; HE580271; CCD24884.1; -; Genomic_DNA.
DR   RefSeq; XP_003670127.1; XM_003670079.1.
DR   STRING; 1071378.G0WAW4; -.
DR   GeneID; 11499085; -.
DR   KEGG; ndi:NDAI_0E00680; -.
DR   eggNOG; ENOG502QQWJ; Eukaryota.
DR   HOGENOM; CLU_003023_1_0_1; -.
DR   OMA; VLKSPKW; -.
DR   OrthoDB; 1984726at2759; -.
DR   Proteomes; UP000000689; Chromosome 5.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 1.20.58.1100; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR   PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR   Pfam; PF00168; C2; 1.
DR   SMART; SM00239; C2; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000689}.
FT   DOMAIN          607..727
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          828..955
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          1035..1173
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
SQ   SEQUENCE   1287 AA;  148407 MW;  0DB73EE70BC90254 CRC64;
     MQRISSSSSS ILSNINFRDL SSLRPDVQRN DVYWDVLKIL LFEYIHEPRF AKEFVQTGVL
     RETRTPELNS MRNNRLSFIQ TDLNVQNTVI DEQAIVRSIT PKLESYLRSV IMRKSGNDIQ
     DILLRGSLSK FYNDLYMDPA MNIRLPSMTL EEIIGYFTKT SANVVSKQNV KNIPQIIESH
     TKYFIGKLIT MLPPNSSPGI VSRLKTYDQT IGKSKSFRIK PPYPPSLKNM AVISPDFVLD
     NITHATYFQK LFGADPLVLQ QDIIKLVPTV KDDVYCHDLK LLLDQIKKDK GPMKSSDFET
     SQQFKLWYNY EFGELTSLLQ TYGGKSVTLD INIPLRIIPN RPRESFVYLL CLILNLESKT
     DPSSLALSHS ASFFMNKCAK YWRIDFETTI STLYYTAANL SRLNNEFFNL ELTPNLYNVI
     FGKFLNAASY DVRYWNRIDK EQWLINYYYT MDQCINSIND AFKRLCSEKR VDYSIPWVFY
     CNNAKLGNTM DILCEECGDI KRLWSKKLKK TVHEASTQFY FSLLEKVPKG PDIEFQHLQN
     VAEDIYLKIK SIYTGYKKEH FELLGGIHIP EEVTKVLVQA IVVDVGSMVQ QVEKQTKKIK
     MKKYGPTDAL SFYSSVKDLI GLYQDFGITK KLNSIERYFE KYLVELCGTT CSKFLEVITS
     SLQKEKWEPI NAEIRYSYSV VDIFKMLNES LSMFLNFEWG NEYQISKILT MLLKSFSDGL
     YVYTENVLRL IQVDLNSVES KSTSNEARNT ISTQLEEDKA SRKFNIWSFN GMKNAINKKE
     YAPVPDPYEY KIRTCIILNN IEKMKSNLND LEDRVQPEKI TKFINHYEKN HKDLKEIANE
     QVKKLHHLYT IRIIEAKDIK GFSKSGLSNA MLSLQDMKQR KEISCTKIIS KTTNPIWDEE
     VELMVPYNEK RELLLTVWHH PTSKFKSVGG DEICGKAQLI LSKKKFLDDG YPNAVELNLD
     QQGTLSLQIS LETEKMDATF SLGKAYRTLS RTSDRIIELM VSKFSPFIKY SLSRENLMKL
     HGNSGQEGAT ESKIGDALLP LFDYLNANLG ILSSQLSETL LLAIMSKAWS EILTTADILL
     LPSLSSSDHK HRLRSARSSI WNSSTLDIVG YGRPLTPLEQ ATIFMWLSNL GIEFFHNDGQ
     GLPMTEVENA YYQNLKKIPH FYEMSVRDLK AATNDLMTDY VKHLKLIYSN KNYGTSVKRI
     GTTVERQKTI MANATKLKRQ QIREEIQKEQ VDPLEQSVEA LKIVLRILIT KGESDYVHKC
     VKQQIKEKKQ LSLQMKLDAA IQGKIVK
//