ID   G0WJG4_TRYCO            Unreviewed;       702 AA.
AC   G0WJG4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Trans-sialidase {ECO:0000313|EMBL:CCD30509.1};
DE   Flags: Fragment;
GN   Name=TS1b {ECO:0000313|EMBL:CCD30509.1};
OS   Trypanosoma congolense.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Nannomonas.
OX   NCBI_TaxID=5692 {ECO:0000313|EMBL:CCD30509.1};
RN   [1] {ECO:0000313|EMBL:CCD30509.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Koliwer-Brandl H., Gbem T.T., Waespy M., Reichert O., Mandel M.,
RA   Drebitz E., Dietz F., Kelm S.;
RT   "Biochemical characterization of trans-sialidase TS1 variants from
RT   Trypanosoma congolense.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCD30509.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Gbem T.;
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; HE583284; CCD30509.1; -; Genomic_DNA.
DR   AlphaFoldDB; G0WJG4; -.
DR   SMR; G0WJG4; -.
DR   VEuPathDB; TriTrypDB:TcIL3000.A.H_000007400; -.
DR   VEuPathDB; TriTrypDB:TcIL3000_0_12970; -.
DR   SABIO-RK; G0WJG4; -.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR008377; Sialidase_trypan.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   PRINTS; PR01803; TCSIALIDASE.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          111..438
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCD30509.1"
FT   NON_TER         702
FT                   /evidence="ECO:0000313|EMBL:CCD30509.1"
SQ   SEQUENCE   702 AA;  76654 MW;  7EA3FF3EC7641867 CRC64;
     QCCDHMHATA AVGTTHQALL WGSKWALRNK TTPKDGEVWW SNPQPGWKEV YDDEWEEWFM
     EQKGPTGVNG VRTEWYRRMK DGYILVGGPK LNSPDMNSTG TTMRTVHSYR IPSIVEVGGV
     LMCVGDARYI TSTDYFFTDT VAAYSTDGGR TWKREVIIPN GRVDAHYSRV VDPTVVAKGN
     NIYVLVGRYN VTRGYWHNKN NRAGVADWEP FVYKGTVNVG TKDNATDVSI SWERTALKSL
     YNFPVSGSPG TQFLGGAGGG VVTSNGTIVL PVQARNKANR VVSMILYSAD DGKSWHFGKG
     EAGVGTSEAA LTEWDGKLLI SARSDGGQGY RMIFESSDLG ATWKEMLNSI SRVIGNSPGR
     SGPGSSSGFI TVTVEGVPVM LLTHPKNLKG SYYRDRLQMW MTDGNRMWHV GQVSEGDDNS
     AYSSLLYTPD GVLYCLHEQN IDEVYSLHLV RLVDELKSIK STALVWKAQD ELLLGNCLPG
     DKYDPGCDGI PTAGLAGLLV GPLTEKTWPD AYRCVNAATS GAVSTAEGVR LDVGGGGHVV
     WPVSEQGQDQ RYYFTNSEFT LAVTVRFDEM PQGELPLLGF VNREGKVKKI LKVSLSGVEW
     LLAYGNEYNS TAAEPLDVNE SHQVVLALHD GIVSLHVDGG NTTATVSVRV ASPAELLNIH
     HLFVGTPVDG GAKEHANITV SNVLVYNRPL RGVELLGLFA NR
//