ID G0XS94_COWPX Unreviewed; 349 AA.
AC G0XS94;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=TNF alpha receptor-like protein {ECO:0000313|EMBL:ADZ24008.1};
GN ORFNames=CPXV_AUS1999_867_003 {ECO:0000313|EMBL:ADZ24008.1},
GN CPXV_AUS1999_867_216 {ECO:0000313|EMBL:ADZ24217.1};
OS Cowpox virus (CPV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10243 {ECO:0000313|EMBL:ADZ24008.1, ECO:0000313|Proteomes:UP000174976};
OH NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH NCBI_TaxID=9913; Bos taurus (Bovine).
OH NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH NCBI_TaxID=10090; Mus musculus (Mouse).
OH NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN [1] {ECO:0000313|EMBL:ADZ24008.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Austria 1999 {ECO:0000313|EMBL:ADZ24008.1};
RA Sammons S.A., Carroll D.S., Meyer H.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADZ24008.1, ECO:0000313|Proteomes:UP000174976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Austria 1999 {ECO:0000313|EMBL:ADZ24008.1};
RA Carroll D.S., Emerson G.L., Li Y., Sammons S., Olson V., Frace M.,
RA Nakazawa Y., Czerny C.P., Tryland M., Kolodziejek J., Nowotny N.,
RA Olsen-Rasmussen M., Khristova M., Govil D., Karem K., Damon I.K., Meyer H.;
RT "Chasing Jenner's Vaccine: Revisiting Cowpox Virus Classification.";
RL PLoS ONE 6:E23086-E23086(2011).
CC -!- SIMILARITY: Belongs to the orthopoxvirus OPG002 family.
CC {ECO:0000256|ARBA:ARBA00034724}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; HQ407377; ADZ24008.1; -; Genomic_DNA.
DR EMBL; HQ407377; ADZ24217.1; -; Genomic_DNA.
DR Proteomes; UP000174976; Genome.
DR GO; GO:0005031; F:tumor necrosis factor receptor activity; IEA:InterPro.
DR GO; GO:0019049; P:virus-mediated perturbation of host defense response; IEA:InterPro.
DR CDD; cd15839; TNFRSF_viral; 1.
DR Gene3D; 2.60.240.20; -; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR010806; Poxvirus_TNF-rcpt-II_C.
DR InterPro; IPR011172; Poxvirus_TNF_rcpt-II.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR034059; TNFRSF_N_viral.
DR PANTHER; PTHR47386; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B; 1.
DR PANTHER; PTHR47386:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B; 1.
DR Pfam; PF07190; CrmD_SECRET; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR PIRSF; PIRSF001790; TNF_C22L; 1.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Receptor {ECO:0000313|EMBL:ADZ24008.1}.
FT REPEAT 31..65
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 31..65
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 67..108
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 67..108
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DISULFID 44..57
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 47..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 68..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 90..108
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 349 AA; 38155 MW; F86E311772C7A7B3 CRC64;
MKSVLYSYIL FLSCIIINGR DIAPYAPSNG KCKDNEYKRH NLCCLSCPPG TYASRLCDSK
TNTRCTPCGS GTFTSRNNHL PACLSCNGRC DSNQVETRSC NTTHNRICEC APGYYCLLKG
SSGCKACISQ TKCGIGYGVS GHTPTGDVIC SPCGLGTYSH TVSSADKCEP VPSNTFNYID
VEINLYPVND TSCTRTTTTG LSESISTSEL TITMNHKDCD PVFRDGYFSV LNKVATSGFF
TGENRYQNIS KVCTLNFEIK CNNKDSSSKQ LTKTKNDNTI MPHSETVTLV GDCLSSVDVY
ILYSNTNTQD YETDTISYHV GNVLDVDSHM PGSCDIHKLI TNSKPTHFL
//
