ID   G0XUC4_COWPX            Unreviewed;      1925 AA.
AC   G0XUC4;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   13-SEP-2023, entry version 23.
DE   RecName: Full=CPXV219 protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CPXV_FRA2001_NANCY_206 {ECO:0000313|EMBL:ADZ29536.1};
OS   Cowpox virus (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=10243 {ECO:0000313|EMBL:ADZ29536.1, ECO:0000313|Proteomes:UP000169997};
OH   NCBI_TaxID=10129; Apodemus sylvaticus (European woodmouse).
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1] {ECO:0000313|EMBL:ADZ29536.1, ECO:0000313|Proteomes:UP000169997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=France_2001_Nancy {ECO:0000313|EMBL:ADZ29536.1};
RA   Carroll D.S., Emerson G.L., Li Y., Sammons S., Olson V., Frace M.,
RA   Nakazawa Y., Czerny C.P., Tryland M., Kolodziejek J., Nowotny N.,
RA   Olsen-Rasmussen M., Khristova M., Govil D., Karem K., Damon I.K., Meyer H.;
RT   "Chasing Jenner's Vaccine: Revisiting Cowpox Virus Classification.";
RL   PLoS ONE 6:E23086-E23086(2011).
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DR   EMBL; HQ420894; ADZ29536.1; -; Genomic_DNA.
DR   Proteomes; UP000169997; Genome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007490; Poxvirus_B22.
DR   InterPro; IPR025128; Poxvirus_B22R_C_dom.
DR   InterPro; IPR025133; Poxvirus_B22R_N_dom.
DR   Pfam; PF04395; Poxvirus_B22R; 1.
DR   Pfam; PF13168; Poxvirus_B22R_C; 1.
DR   Pfam; PF13169; Poxvirus_B22R_N; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        1863..1886
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..105
FT                   /note="Poxvirus B22R protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13169"
FT   DOMAIN          905..1097
FT                   /note="Poxvirus B22R protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13168"
FT   REGION          141..164
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          658..678
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          697..806
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        697..713
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        728..746
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        755..783
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1925 AA;  216109 MW;  E1335BA3F00C4A96 CRC64;
     MNLQRLSLAI YLTATCSWCY ETCMRKTALF HDNQLGHAED NQDSVASLPY KYLQVVNKRE
     RSRLLATFNW TSIAEGVRND FIRICDINGT YLYNYTIAVS MIIDSTEELL PTVTPITTYE
     PSTYNYTIDN GTVSTTEELK VTPSPTPTYA PVTTPLPTSS VPYDQRSNNN VSTISIQILS
     KILGVNETEL TNYLITHKNA TVDNNTTNNN ITVNNTTVND ETSDNNTLHG NIGFLEINNC
     YNISVSNASF RITLVNDTSE EIVLMLTGTS SSDTFISSTN ITECLKTLIN NTSNISDVSI
     TQNMNVTSNC DKCSMNLMTS VIPVVKEFNN TLKKIGVKDD KNNTVYNYYN CKLTTDSTCD
     ELINLDEVIN NITLTNIISS SVSTTNSRKR RDLNGEFEFS TSKELDCLYE SYGVSDDVSH
     CFSSPRRRRS DDKQEYTEMK LLDHAKKDLS IDSVIPRGTT HFQVGASGAS GGVVGDSSPF
     QNVKSRASLL AEKIMPRVPT TATEEQLYAT INRQAKLPAG VKSTPFTEAL VSTINQKLSS
     VKEVTYASLT LPKSSGYVHR PSDSVIYSTI RRTRLPSDSD SDFEDIQTVV KEYNERYGRR
     VSRTQSSSSS DFEDIDEVVA EYKQKYGGAS RVRTSSSSSS DFEDIDEVVA EYNQKYGNAM
     TKGRGSPKPD PLYSTVKKTP KSLSAGVDIV TKQTDYSLLP GVNTGSSIVT PLTRRGATRR
     PKRPSTPPRE DLPPLPPNPP RRQLPRGDHS PPQVPQRDYS PPPLPQRGPP PLPPKPVPAI
     PPRDGQPDNK GFSKFVSPRR CRRSTSGVVC GMIQSRPNDD TYSLLQRPKI EPEYAEVGNG
     LPKNNVPVIG NKHSKKYTSS MSKISTKFDK SMAFGTAMLL TGQQAINQQA RSTALIRKDQ
     MSKDEKIFEA VTMTLSTIGS TLTTAGMIAP PLMIAGIGIT AITGIIDTVK DIYYLFSGHE
     KPVDPVVKLF NTYAGLVSDS NKMGVRKCLT PGEDTIIYMA YRNDTSFKQN TEAMALYFLD
     VIDSEILYLN TSNLVLEYQL KVACPIGTLR SVDVDITAYT ILYDTADNIK KYKFVRLATL
     LSKHPVIRLT CGLAATLVIK PYEVSISDMQ LLKMATPGEP ESTRSIPSDV CDKYPLKKFY
     LLAGGCPYDT SQTFIVHTTC SILLRTATWD QFRNRWVLQN PFRQEGTYKQ LFTFSKYDFN
     DTIIDPNGVA GHASFCTNRS SNQCFWSEPM ILEDVSSCSS RTRKIYVKLG IFNAEGFNSF
     VLNCPTGSTP TYIKDKNADS NNVIIELPVG DYGTAKLYSA TKPSRIAVFC THNYDKRFKS
     DIIVLIFNSI SGIPFSSIYT GSVNGRNRLF TTLSRGMPYR SMYCDNRRPG CYYAGIPFNK
     ESVESDLHYG PEIMLKETYD ANSIDPRVIT KSKTHFPTPI SVKFTVDNLG NGYNKPEKFW
     NDAKSKKRTY SAMTIKILPC TVRNKNVNFG YNYGHIISNM VYAQSTSQDY GDGTNYTFKS
     VNRSDHECES ILDLKAKEVT VMCPAFSIPR NISAYEGLCF SVTTSKDHCA TDNDWLKSRG
     YGKADAIKQR ACFHHWNYAT TSLDYYCSSE NVFKSDWPDY DPCKSYIHIE YRDIWIESKV
     LQQPPYTFEF THDDSNEYVN KEISNKLNDL YNEYKNIMEY SDGSLPASIN RLAKALTSEG
     REIASVNIDG NLLDIAYQAD KEKMADIQNK INDITRDLFI HTLSDKDIKD IIESEEGKRC
     CIIDVKNNRV EKYYPIDNYL CGTLDDYIYT SVEYNKSYVL VNDTYMSYDY LESSGVVVLS
     CYEMTIISLD TKDAKDAIED EIVASAVAEA LNDMFKEFDK NVSAIIIKEE DNYLNSSPNI
     YHIIYIIGGT ILILLVIILI LAIYIARNKY RTRKYKIMKD DTMSIKSEHH NSLETVSMEI
     MDNRY
//