ID G0XY70_STAAU Unreviewed; 542 AA.
AC G0XY70;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 13-SEP-2023, entry version 42.
DE SubName: Full=Clumping factor B {ECO:0000313|EMBL:AEK94141.1};
DE Flags: Fragment;
GN Name=clfB {ECO:0000313|EMBL:AEK94141.1};
OS Staphylococcus aureus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=1280 {ECO:0000313|EMBL:AEK94141.1};
RN [1] {ECO:0000313|EMBL:AEK94141.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Not116 {ECO:0000313|EMBL:AEK94141.1};
RX PubMed=21245656;
RA Murphy E., Lin S.L., Nunez L., Andrew L., Fink P.S., Dilts D.A.,
RA Hoiseth S.K., Jansen K.U., Anderson A.S.;
RT "Challenges for the evaluation of Staphylococcus aureus protein based
RT vaccines: Monitoring antigenic diversity.";
RL Hum. Vaccin. 7:51-59(2011).
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
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DR EMBL; HQ424314; AEK94141.1; -; Genomic_DNA.
DR AlphaFoldDB; G0XY70; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.1280; -; 1.
DR Gene3D; 2.60.40.1290; -; 1.
DR InterPro; IPR011266; Adhesin_Fg-bd_dom_2.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR011252; Fibrogen-bd_dom1.
DR InterPro; IPR041171; SDR_Ig.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; NF033845; MSCRAMM_ClfB; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF17961; Big_8; 1.
DR Pfam; PF10425; SdrG_C_C; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SUPFAM; SSF49401; Bacterial adhesins; 2.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..35
FT /note="YSIRK Gram-positive signal peptide"
FT /evidence="ECO:0000259|Pfam:PF04650"
FT DOMAIN 233..338
FT /note="SDR-like Ig"
FT /evidence="ECO:0000259|Pfam:PF17961"
FT DOMAIN 368..524
FT /note="Fibrinogen-binding"
FT /evidence="ECO:0000259|Pfam:PF10425"
FT REGION 44..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 542
FT /evidence="ECO:0000313|EMBL:AEK94141.1"
SQ SEQUENCE 542 AA; 58790 MW; 1381004B4B4198D8 CRC64;
MKKRIDYLSN KQNKYSIRRF TVGTTSVIVG ATILFGIGNH QAQASEQSND TTQSSKNNAS
ADSEKNNMIE TPQLNTTAND TSDISANTNS ANVDSTAKPM STQTSNTTTT EPASTNETPQ
PTAIKDQATA AKMQDQTVPQ EANSQVDNKT TNDANSIATN SELKNPQTLD LPQSSPQTIS
NAQGTSKPSV RTRAVRSLAV AEPVVNAADA KGTNVNDKVT AKDFQLEKTT FDPNQSGNTF
MAANFTVTGQ VKSGDYFTAK LPDSVTGNGD VDYSNSNNTM PIADIKSTNG DVVAKATYDI
LTKTYTFVFT DYVNNKENIN GQFSLPLFTD RAKAPKSGTY DANINIADEM FNNKITYNYS
SPIAGIDKPN GANISSQIIG VDTASGQNTY KQTVFVNPKQ RVLGNTWVYI KGYQDKIEES
SGKVSATDTK LRIFEVNDTS KLSDSYYADP NDSNLKEVTN EFKDKITYKY QNVASINFGD
ITKTYVVLVE GHYDNTGKNL KTQVIQENID PATGKDYSIF GWNNENVVRY GGGSADGDSA
VN
//
