ID G1KB61_ANOCA Unreviewed; 419 AA.
AC G1KB61;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Mitochondrial chaperone BCS1 {ECO:0000256|ARBA:ARBA00016942};
DE AltName: Full=BCS1-like protein {ECO:0000256|ARBA:ARBA00032816};
GN Name=BCS1L {ECO:0000313|Ensembl:ENSACAP00000002697.1};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002697.1, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002697.1, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002697.1,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002697.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family. BCS1 subfamily.
CC {ECO:0000256|ARBA:ARBA00007448}.
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DR RefSeq; XP_003214988.1; XM_003214940.3.
DR AlphaFoldDB; G1KB61; -.
DR STRING; 28377.ENSACAP00000002697; -.
DR Ensembl; ENSACAT00000002765.3; ENSACAP00000002697.1; ENSACAG00000002750.3.
DR GeneID; 100552242; -.
DR KEGG; acs:100552242; -.
DR eggNOG; KOG0743; Eukaryota.
DR GeneTree; ENSGT00390000005415; -.
DR HOGENOM; CLU_010189_6_2_1; -.
DR InParanoid; G1KB61; -.
DR OMA; WMTLYQR; -.
DR OrthoDB; 664379at2759; -.
DR TreeFam; TF315009; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000002750; Expressed in ovary and 12 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:Ensembl.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IEA:Ensembl.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Ensembl.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IBA:GO_Central.
DR GO; GO:0032979; P:protein insertion into mitochondrial inner membrane from matrix; IBA:GO_Central.
DR CDD; cd19510; RecA-like_BCS1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR014851; BCS1_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23070; BCS1 AAA-TYPE ATPASE; 1.
DR PANTHER; PTHR23070:SF232; MITOCHONDRIAL CHAPERONE BCS1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF08740; BCS1_N; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01024; BCS1_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022792};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..191
FT /note="BCS1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01024"
FT DOMAIN 222..357
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 419 AA; 47313 MW; C67915724DE0689A CRC64;
MPFSDFVVTL KDNPYFGAGF GLVGVGTALA LARKGAQLGM VAFRRHCMIT LEVPSKDKSY
HWLLNWISHH AKHTQHLSVE TSYLQHESGR VSTKFDFIPS PGNHFIWYQR KWIRIERNRE
KQMIDLHTGT PWESVTFTAV GNKREIFFNI LQEAKELALR QQEGKTVMYT AMGAEWRPFG
FPRRRRPLTS VVLEEGVSER IVQDVKEFIG NPKWYIDRGI PYRRGYLLYG PPGCGKSSFI
TALAGELQYS ICLLSLSDRS LSDDRLNHLL SVAPQQSIIL LEDVDAAFVG RDLAAENPNA
YQGMGRLTFS GLLNALDGVA SSEARIVFMT TNYVDRLDPA LVRPGRVDLK QYVGHCSQWQ
LGRMFQRFFP DQPAAMAEQF AMQALSLSNQ ISAAQVQGHF MLHKADPDGA IQNVKTLIS
//
