ID G1KBC5_ANOCA Unreviewed; 1111 AA.
AC G1KBC5;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Catenin delta 2 {ECO:0000313|Ensembl:ENSACAP00000002865.4};
GN Name=CTNND2 {ECO:0000313|Ensembl:ENSACAP00000002865.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000002865.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000002865.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000002865.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000002865.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR AlphaFoldDB; G1KBC5; -.
DR STRING; 28377.ENSACAP00000002865; -.
DR Ensembl; ENSACAT00000002936.4; ENSACAP00000002865.4; ENSACAG00000002855.4.
DR eggNOG; KOG1048; Eukaryota.
DR GeneTree; ENSGT00940000154952; -.
DR HOGENOM; CLU_007897_0_0_1; -.
DR TreeFam; TF321877; -.
DR Proteomes; UP000001646; Chromosome 4.
DR Bgee; ENSACAG00000002855; Expressed in testis and 9 other cell types or tissues.
DR GO; GO:0005912; C:adherens junction; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0014069; C:postsynaptic density; IBA:GO_Central.
DR GO; GO:0045296; F:cadherin binding; IBA:GO_Central.
DR GO; GO:0098609; P:cell-cell adhesion; IBA:GO_Central.
DR GO; GO:0007043; P:cell-cell junction assembly; IBA:GO_Central.
DR GO; GO:0060997; P:dendritic spine morphogenesis; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF9; CATENIN DELTA-2; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 4.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT REPEAT 478..511
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 522..565
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 778..815
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 98..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1111 AA; 121335 MW; C7C6E52A9F801512 CRC64;
FFILLVTPDI EDELTTGLEL VDSCIRSLQE SGILDPQDYT TSERPSLLSQ SALQLNSKPE
GSFQYPSSYH SNQTLALGET ATSQLPARSN QVRSAIQNYS QGTSGRTAHL SGSEPPPPPL
RGSPSRRSHA RVLYYFQIPL AGAERVLSPS SIQQAKWCSP TQLQQGGAAS EGSSGGGYGT
TQRVSSPKQS PSRLAKSYST SSPINIVVST AGLVPSPLRV TSPPTLPPAS SAAASSPLHQ
LSSTLGTYAT LSPTKRLVHP PHSQELYASA TLQRPGSLAA GSRASYTSQH SHLGSDLRSL
QSPEHHIDPI YEDRVYQKPP MRSLSQSQGD PLQPAHTGTY RTSTAPSSPG VDSVPLQRTG
SQHGTQNATA TFQRASYAAG PASNYADPYR QLQYCPSVES PYSKSGPAIP PEGTLARSPS
IDSIQKDPRE FGWRDPELPE VIQMLQHQFP SVQSNAAAYL QHLCFGDNKI KSEIRRQGGI
QLLVDLLDHR MTEVHRSACG ALRNLVYGKA NDDNKIALKN CGGIPALVRL LRKATDLEIR
ELVTGVLWNL SSCDALKMPI IQDALAVLTN AVIIPHSGWE NSPLQDDHKI QLHSSQVLRN
ATGCLRNVSS AGEEARRRMR ECDGLTDALL YVIQSALGSS EIDSKTVENC VCILRNLSYR
LAAETSQGQQ MGTDELDGLL CGDANGKDAE SSGCWGKKKK KKKSQDQWDG VGPLPDCAEP
PKGIQMLWHP SIVKPYLTLL SECSNPDTLE GAAGALQNLA AGSWKWSVYI RAAVRKEKGL
PILVELLRID NDRVVCAVAT ALRNMALDVR NKELIGKYAM RDLVHRLPGG NSSNNSGSKA
MSDDTVTAIC CTLHEVITKN MENAKALRDA GGIEKLVGIS KSKGDKHSPK VVKAASQVLN
SMWQYRDLRS LYKKDGWSQY HFVASSSTIE RDRQRPYSSS RTPSISPVRM SPNNRSASAP
ASPREMISLK ERKTDYESTG TNATYHGSKG EHTSRKDTMT AQNTGISTLY RNSYGAPAED
IKHNQVSTQP VPQEPTRKDY EPYQPFQNST RNYDESFFED QVHHRPPASE YNMHLGLKST
GNYVDFYSAA RPYSELNYET SHYPASPDSW V
//
