ID G1KI41_ANOCA Unreviewed; 1097 AA.
AC G1KI41;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=CTR9 homolog, Paf1/RNA polymerase II complex component {ECO:0000313|Ensembl:ENSACAP00000008555.3};
GN Name=CTR9 {ECO:0000313|Ensembl:ENSACAP00000008555.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000008555.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000008555.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000008555.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000008555.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1KI41; -.
DR STRING; 28377.ENSACAP00000008555; -.
DR Ensembl; ENSACAT00000008738.4; ENSACAP00000008555.3; ENSACAG00000008611.4.
DR eggNOG; KOG2002; Eukaryota.
DR GeneTree; ENSGT00390000005097; -.
DR HOGENOM; CLU_006386_0_0_1; -.
DR InParanoid; G1KI41; -.
DR TreeFam; TF314342; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000008611; Expressed in hindlimb bud and 13 other cell types or tissues.
DR GO; GO:0016593; C:Cdc73/Paf1 complex; IBA:GO_Central.
DR GO; GO:0000791; C:euchromatin; IEA:Ensembl.
DR GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR GO; GO:0001711; P:endodermal cell fate commitment; IEA:Ensembl.
DR GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IEA:Ensembl.
DR GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0007259; P:receptor signaling pathway via JAK-STAT; IEA:Ensembl.
DR GO; GO:0019827; P:stem cell population maintenance; IEA:Ensembl.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IBA:GO_Central.
DR CDD; cd22249; UDM1_RNF168_RNF169-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR031101; Ctr9.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14027; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9; 1.
DR PANTHER; PTHR14027:SF2; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF14559; TPR_19; 3.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 10.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 116..149
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 259..292
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 415..448
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 449..482
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 815..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 746..803
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 815..836
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..873
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..899
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..946
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1017
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1067
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1089
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1097 AA; 124482 MW; 535A567AE89F1472 CRC64;
MTCLDTLAAY YVQQARKEKN KDNKKELITQ ATLLYTMADK IIMYDQNHLL GRACFCLLEG
DKMDQADAQF HFVLNQSPNN IPALLGKACI SFNKKDYRGA LAYYKKALRT NPGCPAEVRL
GMGHCFVKLS KLEKARLAFS RALELNSKCV GALVGLAVLE LNNKEADSIK NGVQLLSRAY
TIDPSNPMVL NHLANHFFFK KDYGKVQHLA LHAFHNTEVE AMQAESCYQL ARSFHVQEDY
DQAFQYYYQA TQFASSSFVL PFFGLGQMYI YRGDKENASQ CFEKVLKAYP NNYETMKILG
SLYAASEDQD KRDIAKGHLK KVTEQYPDDV EAWIELAQIL EQTDIQGALS AYGTATRILQ
EKVQADVPPE ILNNVGALHF RLGNLGEAKK YFLASLDRAK AEAEHDEHYY NAISVTTSYN
LARLYEAMCE FHEAEKLYKN ILREHPNYVD CYLRLGAMAR DKGNFYEASD WFKEALQINQ
DHPDAWSLIG NLHLAKQEWG PGQKKFERIL KQPSTQNDTY SMLALGNVWL QTLHQPTRDR
EKEKRHQDRA LAIYKQVLRN DPKNLYAANG IGAVLAHKGY FREARDVFAQ VREATADISD
VWLNLAHIYV EQKQYISAVQ MYENCLRKFY KHQNTEVLLY LARALFKCGK LQECKQTLLK
ARHVAPSDTV LMFNVALVLQ RLATSVLKDE KSNLKEVLNA VKELELAHRY FSYLSKVGDK
MRFDLALAAT EARQCSDLLS QAQYHVARAR KQDEEERELR AKQEQEKELL RQKLLKEQEE
KRLREIEEQK KLLEQRAQYV EKTKNILMFT GEVEGSKEKK RGGAGRRSRK TGEFEEFVND
DSDDDLPVSR KKKRRKGSGS EQDGEEEDGE KKKKKRRRAQ KADDGTDDDD NEATPRPKKR
RPAKTEKRKP KPERLPPSMK GKIKSKAIIS SSDDSSDEDK LKIADDGNAR NSNSDSDNAE
TLNKRVMSDS DSDNSNRSGS ERGSPRRPAA HPSDEDSDSD GPPRKKRQSD SDQSDNDSVR
SGRSPSVRSG RSPSVQSGRS HSGGSENESR PASRSADSDR DSERASDNEG SVNGSEPEAS
NNEGSERGSY AGSDDSD
//
