ID G1KM57_ANOCA Unreviewed; 317 AA.
AC G1KM57;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Epiphycan {ECO:0000313|Ensembl:ENSACAP00000012095.1};
GN Name=EPYC {ECO:0000313|Ensembl:ENSACAP00000012095.1};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000012095.1, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000012095.1, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000012095.1,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000012095.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small leucine-rich proteoglycan (SLRP)
CC family. SLRP class III subfamily. {ECO:0000256|ARBA:ARBA00006912}.
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DR RefSeq; XP_003221176.1; XM_003221128.3.
DR AlphaFoldDB; G1KM57; -.
DR STRING; 28377.ENSACAP00000012095; -.
DR Ensembl; ENSACAT00000012340.3; ENSACAP00000012095.1; ENSACAG00000012287.3.
DR GeneID; 100560848; -.
DR KEGG; acs:100560848; -.
DR CTD; 1833; -.
DR eggNOG; KOG0619; Eukaryota.
DR GeneTree; ENSGT00940000157574; -.
DR HOGENOM; CLU_067583_0_0_1; -.
DR InParanoid; G1KM57; -.
DR OMA; NFISEIH; -.
DR OrthoDB; 1080036at2759; -.
DR TreeFam; TF351924; -.
DR Proteomes; UP000001646; Chromosome 5.
DR Bgee; ENSACAG00000012287; Expressed in dewlap.
DR GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR GO; GO:0061975; P:articular cartilage development; IBA:GO_Central.
DR GO; GO:0060348; P:bone development; IBA:GO_Central.
DR GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR InterPro; IPR043547; Mimecan/Epiphycan/Opticin.
DR PANTHER; PTHR46269:SF3; EPIPHYCAN; 1.
DR PANTHER; PTHR46269; EPIPHYCAN-RELATED; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..317
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003413277"
FT DOMAIN 112..142
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT REGION 73..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 36365 MW; 1E6FD7F60AF016FE CRC64;
MKSFPNIFLA IFLFDAIMAA PTMSSINYDS ETYDVTLEDL DILYDYDENL SVDQTQTEIG
TISPSITGEI YLPPPLPEDT EEEEASTPKL IDGSSPHEPG VLSPHTHEGL PTCLLCTCMS
TSVYCDDREL EALPPLPKET THFYSRYNRI KKVNRDDFAN LSHLKRIDLT SNFISEMDED
AFRNLPQLQE LILRDNRIRQ LPELPPTLTF IDISNNILGR KGIKQEAFKD MSQLHYLYIT
DNNLDHIPLP LPENLQSLHL QNNNIQEMHE DTFCKMKDYS YIRKSLEDIR LDGNPINLSK
TPYAYMCLPR LPVGSLF
//
