ID G1KNT6_ANOCA Unreviewed; 730 AA.
AC G1KNT6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Adenylate kinase 7 {ECO:0000313|Ensembl:ENSACAP00000013221.3};
GN Name=AK7 {ECO:0000313|Ensembl:ENSACAP00000013221.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000013221.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000013221.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000013221.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000013221.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003214371.1; XM_003214323.3.
DR AlphaFoldDB; G1KNT6; -.
DR STRING; 28377.ENSACAP00000013221; -.
DR Ensembl; ENSACAT00000013487.4; ENSACAP00000013221.3; ENSACAG00000013423.4.
DR GeneID; 100562329; -.
DR KEGG; acs:100562329; -.
DR CTD; 122481; -.
DR eggNOG; KOG3078; Eukaryota.
DR GeneTree; ENSGT00390000015102; -.
DR HOGENOM; CLU_015567_1_0_1; -.
DR InParanoid; G1KNT6; -.
DR OrthoDB; 5483389at2759; -.
DR TreeFam; TF313982; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000013423; Expressed in embryonic post-anal tail and 11 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004017; F:adenylate kinase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004127; F:cytidylate kinase activity; IBA:GO_Central.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 1.
DR CDD; cd22967; DD_AK7; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR047499; DD_AK7.
DR InterPro; IPR007858; Dpy-30_motif.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF105; ADENYLATE KINASE 7; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00406; ADK; 1.
DR Pfam; PF05186; Dpy-30; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 370..401
FT /note="ATPase AAA-type core"
FT /evidence="ECO:0000259|Pfam:PF00004"
FT COILED 423..461
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 625..682
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 730 AA; 84061 MW; DF1ECA851A484736 CRC64;
MSEEEEAVAE AEEIIRNQRI FLNHLDSYCG RNIGKYLSNA IVGASLDEIA EEEEEEDEGR
SAAEVLPPKP KEGLYQIVGT LSQATDKKPD FAVEAYSTTS RDELLARMLE CDIIIYNITE
DAKQTEEATW AATVLNEESV NFEKQKVFIL LSTIMTWARS KPLDPDDPEI PFTEEDYRRR
KHHPNFIEHT NAEKTIIKLG KNNKSKFATY VVASGLQYGA EERLLHYFFK LSWLGEVPMI
PIFGDGRNFI PAIHIVDLAA VLQNVADHRP RTHYIIAVDE SIHTLGEIVR SISKNVGPGK
TQKIPKDSAF LNKDLTQAHL DELLVNLRME AVILKETFNI KWVSQGGIVE NIEQIVNEYK
QSRGLLPIKM CVLGPPGVGK TSIAEQLCKH YKVHHIKIKE VITKAIENLE KIIAPKDIPE
TILEEEEEEE EEEEAEEGDN IEEAQELLDA VKENMEQNAG RIDDQYVIRF MRETLTSMPC
RNQGYVLDGF PKTYELAKDL FNLEEEEEED DSRGKIHHFD KVITPDFIVS LNAPDEFLKN
RIMNLPESVV AGTHYAQDRY LRALSLFREL NTEDETVLNY FDEIEMHPQH IDVSKFEGLE
NSVIVREIIK NVGEPRNYGL TDEELEEFER KQAEERLARE AKEKADLEKK EADERAQKLA
NWEEWNKRLD EVKRQEQELL EAQSIPLRNY LMKHVMPTLM QGLNQCCMVR PDDPVDFLAE
YLFKNNPEFD
//
