ID G1KQK8_ANOCA Unreviewed; 1508 AA.
AC G1KQK8;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=PHD and ring finger domains 1 {ECO:0000313|Ensembl:ENSACAP00000014763.3};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000014763.3, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000014763.3, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000014763.3,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000014763.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 28377.ENSACAP00000014763; -.
DR Ensembl; ENSACAT00000015064.3; ENSACAP00000014763.3; ENSACAG00000015010.3.
DR eggNOG; KOG0825; Eukaryota.
DR GeneTree; ENSGT00950000183205; -.
DR HOGENOM; CLU_003222_0_0_1; -.
DR InParanoid; G1KQK8; -.
DR TreeFam; TF332183; -.
DR Proteomes; UP000001646; Chromosome 1.
DR Bgee; ENSACAG00000015010; Expressed in forelimb bud and 13 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16635; mRING-HC-C3HC3D_PHRF1; 1.
DR CDD; cd15536; PHD_PHRF1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR047157; PHRF1-like.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12618; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12618:SF20; PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 73..114
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 150..200
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 16..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 613..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1382..1417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..52
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..322
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..346
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..896
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..942
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..978
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1005
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1006..1023
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1045
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1075
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1391..1405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1508 AA; 167204 MW; 7C78EDD61D292E34 CRC64;
MNTHVKSAFV CSCLKESTDG SSADSDDTGS GEEDDIDEDG GEEDEEGEDE DLEAKPQFNG
GVASSSDEDA ENCPICLNTF RDQAVGTPEN CAHYFCLDCI VEWSKNANSC PVDRIIFKSI
CVRVRFGGEI LKKIPVQNTK SQEDEVEDDP TFCEVCGRSD REDRLLLCDG CDAGYHMECL
NPPLSEIPVD EWFCPPCAPT NATPVDADRV SEEEVASLIA DVTPTTSRLR PNVRTRAIAR
TRQSERVRAT VNRNRITTAQ RIQHVPRYLM SSLLDETIEA VAAGLSTAVY QRPLIPRSTT
KKKRKRGRRK RTAGKKIHAK SSAGKKSGGT WIKRRKRRKH RRVNKVKTEV TARSRIAKTL
RLGKPVRGTS IPSVYKPVEP SLGLMRADIG AASLSVFGDP FELDPYNSND ELPVANSPLS
TKRRGLSQSA LRSHRPVARP VAVGIPGRSV PAFSPEPEVE AAPVPDLLGS ILTGQSLLMM
SGSDVVINRD GSLTAKRTSK VSSSDTESSK LKPSTSHTCI SSPSSLSVTN RDVSPLSQTT
SGRTPIRFEY SMTPRSVQTQ NLASLNRCGP KCTSSCIFKP LNSSSSSTSK AMSVKEPLKS
SPKRLEISEL PRIPKIKKET TNGHLGSQPA SDRSGDIPSA CITQLTGKGN ANQPIRSSKM
ESGISSASHQ QGQTSGGSAS TVARDGGSTL PPARGKVGSS SFQSFKINIP GNIGHSSRLS
NPGFCNTFRP VDNKVQQKEN PSPLFSLKKT KPIKSEIYDP FDPTGSDSSS TNSSPERLPF
ANITRTISIA SPKAQTFQTV RRITPYNLEN IFGLEAESTD VPSATTESCD DVMLKERLVE
QVPDAVQVKH EEEELWSFSR SPSNSSSESK KKIKRKKVPM KDHKSTHPRS RSRTHSRDKT
RQPPRDRSSS HERSRKKKAK DKTKDKKAKS SWPKEHKRAR SRSVSPGNSS FELYENRKKK
KHSDPGVRGR EYSHSNNAER TKKKKHRRER SYDRLEKDGS SRSRERKRSR SRSQEKRKRK
SRSPSSRSQE SKGSKPRERQ LPSRSRSKER KHKSKEVSPQ LLKEEGQRSS DDNLDCSLEH
APNWSHELGC MSPETLNVPS DLIPEQEVPP EDDIMEADLK GGIKTEQVCE ELEHETLPAQ
QDHSSSEVFL DNLDSPTGIE LAVGYESPRS DSQITVKMEE IEIKIEDDDV CPFFSDSVLL
KKGKPVSGHD EVTPFPTLSE IKRPTEVKCE LPMLDENIGD ANKSELEAAV QGPLLKSKAP
VKRVTWNLQE EESNIAAADK TPRMAFCKQQ RTNEGVWKAE DLTQTLNQVQ LTEPLPTNYM
VPEPMFPDLD SNQVYNQNLP LMAPLPSNLP PYAPVSQPTV QFIMQGSLPL LSCVASQGLT
PEPGNLATAS EPGIQAASTG EAEETVKTPK SPVDKTKNEE YMKKLHMQER AVEEVKLAIK
PFYQKREITK EEYKEILRKA VQKICHSKSG EINPVKVANL VKAYVEKYKH MRKHKKTDAE
EEPRETGN
//
