ID G1KTD9_ANOCA Unreviewed; 497 AA.
AC G1KTD9;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Growth arrest specific 7 {ECO:0000313|Ensembl:ENSACAP00000016722.4};
GN Name=GAS7 {ECO:0000313|Ensembl:ENSACAP00000016722.4};
OS Anolis carolinensis (Green anole) (American chameleon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Iguania; Dactyloidae; Anolis.
OX NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000016722.4, ECO:0000313|Proteomes:UP000001646};
RN [1] {ECO:0000313|Ensembl:ENSACAP00000016722.4, ECO:0000313|Proteomes:UP000001646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000016722.4,
RC ECO:0000313|Proteomes:UP000001646};
RG The Genome Sequencing Platform;
RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSACAP00000016722.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008102534.2; XM_008104327.2.
DR AlphaFoldDB; G1KTD9; -.
DR STRING; 28377.ENSACAP00000016722; -.
DR Ensembl; ENSACAT00000017052.4; ENSACAP00000016722.4; ENSACAG00000016997.4.
DR GeneID; 100557413; -.
DR KEGG; acs:100557413; -.
DR CTD; 8522; -.
DR eggNOG; KOG0940; Eukaryota.
DR eggNOG; KOG2398; Eukaryota.
DR GeneTree; ENSGT00940000156268; -.
DR HOGENOM; CLU_052182_0_1_1; -.
DR InParanoid; G1KTD9; -.
DR Proteomes; UP000001646; Chromosome 2.
DR Bgee; ENSACAG00000016997; Expressed in testis and 13 other cell types or tissues.
DR GO; GO:0005884; C:actin filament; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0030041; P:actin filament polymerization; IBA:GO_Central.
DR GO; GO:0048812; P:neuron projection morphogenesis; IBA:GO_Central.
DR CDD; cd07649; F-BAR_GAS7; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR037957; GAS7_F-BAR.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR23065:SF57; GROWTH ARREST-SPECIFIC PROTEIN 7; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF16623; WW_FCH_linker; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT DOMAIN 99..132
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 217..477
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 329..388
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 91..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 57058 MW; 727301544D5ADBF3 CRC64;
MDLFNFQRSQ LSKGKCQRVL TCKRKGGSFL LLFQILGNAL TPYSYTQRGT QASDSCTAHL
AKRARPAMDC DCISARDLAK ASVKPRKIIS QGGEDSQNGH LPPGWQSYMS PQGRRYYVNT
FTNETTWERP SSVPGTPKSP VTQKNSLPTV NGYHIPGTLV PQLESSHMSL RKVGNDPQSP
GSPSPTRKQN KETTFTINCV TFPHPDAMPE QQLLKPSEWS YCDYFWTDKK DPQGNSTVSG
FEILLQKQLK GKQMQKEMAE FIRERIKIEE EYAKNLSKLS QSSLAAQEEG TLGESWSQLK
KSLADEAEVH LKFSSKLQGE VEKPLLNFRE NFKKDMKKYD HHIADLRKQM VSRYAAVEKA
RKALSERQKD LELKTQQLEI KLSNKTEEEI KKARRKSTQA GDDLMRCVDL YNQAQSKWFE
EMVTTSLELE RLEVERVEMI RQHLCQYTQL RHETDMFNQS TVEPVDQLLQ KVDPAKDREL
WVKEHKTGDI RPVDMEI
//
