ID G1L6I0_AILME Unreviewed; 1027 AA.
AC G1L6I0;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Leucine rich repeat and coiled-coil centrosomal protein 1 {ECO:0000313|Ensembl:ENSAMEP00000002495.2};
GN Name=LRRCC1 {ECO:0000313|Ensembl:ENSAMEP00000002495.2};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000002495.2, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000002495.2, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000002495.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G1L6I0; -.
DR STRING; 9646.ENSAMEP00000002495; -.
DR Ensembl; ENSAMET00000002603.2; ENSAMEP00000002495.2; ENSAMEG00000002378.2.
DR eggNOG; KOG0531; Eukaryota.
DR GeneTree; ENSGT00940000157414; -.
DR HOGENOM; CLU_011297_1_0_1; -.
DR InParanoid; G1L6I0; -.
DR TreeFam; TF329470; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45973:SF13; LEUCINE RICH REPEAT AND COILED-COIL CENTROSOMAL PROTEIN 1; 1.
DR PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 312..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 418..455
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 481..637
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 779..943
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 981..1026
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1027 AA; 119209 MW; FB55FBB93952493E CRC64;
MEAPVEAEVE NEDGDSSCGD LCFMDKGLRS ISELSLDSSL HAINLHCNNI SKIEAIDHLW
NLQHLDLSSN QINQIEGLNT LTKLCTLNLS CNLITRIEGL EALTNLTRLN LSYNHINDLS
GLIPLHGIKH KLRFIDLHSN CIDSIHHLLQ CVVGLNFLTN LILEKNGDDN PVCHVPGYRA
IMLQTLPQLR ILDCKNIFGE PVNLSEINSS RLQCLEGLLN NLVSSDSPLN TSEDEIIDSM
PVVTPPIDEI APLDQFASPT DTGLTSFISI CPSSEPEKVN HKNSFHNDMK LQKLDDQILQ
LLTETSDSLI DNVPEKDLRP KRDTDMTSES DYGNRKECNR RIPRRSKIPY YSKTIQTIKH
HHKNNNPFMS CNRKMKPPFF KDLYVRSSLA NCNMLEESEE QKTEIIKVDN SSLEDTTYRT
LLEQLDQERE KRWKAEQAEK KLMDYIAELH KHANEKKDIH SLALLTTDRL REIIFKERNS
KVQLEVMVHK LQNEIKKLTI ELIKARDQQE DHIRHLRTLE KALEKMERQK GQQQAAQMRL
IQEVELKAAA ADTEINLLRT SLHQEKEQVQ QLHELLALKE QEHRKELETR EFFSDAEFQE
ALAKEVAKEE RKHEQDIKEY QEKIDTLNQQ YMDLENEFRI ALTVEARRFK DVKDGFENVA
TELAKSKHAL VWAQRKENES SSLIKDLTCM VKEQKTKLAE VSKLKQETAA NLQNQISTLE
ILIEDDKQKS IQIELLKHEK VQLISELAAK ESLIYGLRTE RKVWGHELAQ HGSSLALDRG
KLEAQIESLY RENESLRKKN ECDNDALRIK CKIIEDQTET IGKLKACVQE REEQIKILQE
KITEIQKCTQ EQLDEKSSQL DDIIEKLERH NERKEKLKQQ LKVKELELEE IRKAYSTLNQ
KWHDKGELLS HLEMQVKEVK EKFENKERKL KAERDKSIEL QKDAVEKLHS MDDAFKKQVD
AIVEAHHAEI IQLASEKQKY IDSANLKVHR VEEEMRELLQ ETCKNKKAME EKIRQLAFAL
TEIQQEM
//
