ID G1MJ74_AILME Unreviewed; 1460 AA.
AC G1MJ74;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Regulatory factor X7 {ECO:0000313|Ensembl:ENSAMEP00000019409.1};
GN Name=RFX7 {ECO:0000313|Ensembl:ENSAMEP00000019409.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|Ensembl:ENSAMEP00000019409.1, ECO:0000313|Proteomes:UP000008912};
RN [1] {ECO:0000313|Ensembl:ENSAMEP00000019409.1, ECO:0000313|Proteomes:UP000008912}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
RN [2] {ECO:0000313|Ensembl:ENSAMEP00000019409.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002922988.1; XM_002922942.3.
DR RefSeq; XP_019659021.1; XM_019803462.1.
DR STRING; 9646.ENSAMEP00000019409; -.
DR Ensembl; ENSAMET00000020176.2; ENSAMEP00000019409.1; ENSAMEG00000018368.2.
DR GeneID; 100483947; -.
DR KEGG; aml:100483947; -.
DR CTD; 64864; -.
DR eggNOG; KOG3712; Eukaryota.
DR GeneTree; ENSGT01050000244970; -.
DR HOGENOM; CLU_252972_0_0_1; -.
DR InParanoid; G1MJ74; -.
DR OMA; MSMNSSH; -.
DR OrthoDB; 2961139at2759; -.
DR TreeFam; TF321340; -.
DR Proteomes; UP000008912; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR Gene3D; 6.10.140.1290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR040889; RFX5_N.
DR InterPro; IPR047009; RFX5_N_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF2; DNA-BINDING PROTEIN RFX7; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF18326; RFX5_N; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008912}.
FT DOMAIN 108..183
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 634..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 918..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..963
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 964..1015
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 157385 MW; 90C07FC24204896D CRC64;
MAEEQQQPPP QQPDAHQQLP PSAPNSGVAL PALVPGLPGT EASALQHKIK NSICKTVQSK
VDCILKEVEN FTDLEKLYLY LQLPSGLSNG EKSDQNAVSS SRAQQMHAFS WIRNTLEEHP
ETSLPKQEVY DEYKSYCDNL GYHPLSAADF GKIMKNVFPN MKARRLGTRG KSKYCYSGLR
KKAFVHMPTL PNLDFHKTGD GLEGTEPSGQ LQNIDEEVIS SACRLVCEWA QKVLSQPFDT
VLELARFLVK SHYIGTKSMA ALTVMAAAPP GIKGITQASA FIPTAESNSF QPQVKTLPSP
IDAKQQLQRK IQKKQQEQKL QSPLPGESSG KKPEGATTNG VTNLSNGNPA ILSPQPIGIV
VAAVPSPIPV QRTRQLVTSP SPMSSSDGKV LPLNVQVVTQ HMQSVKQAPK TPQNVPASPG
GDRSARHRYP QILPKPANTS ALTIRSPTTV LFTSSPIKTA VVPTSHMSSL NVVKMTAISL
TPSNSSAPLK HSASVNSATG TIEESRTIPQ IKNGSVVSLQ SPGSRTSSTG GTSAVEVKVE
PETSSDEHPV QCQENSDGTK APKTTPSALL GQKSNTDGVV QKPSNEGVVE VKSTKVCDQR
TKCKSRCNET QPGTSTGNNP STVTLPVATQ NLTFTSTSSP ANGDSINKDP KLCTKSPRKR
LSSALQESQV PPIKKPIVEQ LSAVIIEGQK PGSVEKDQKV PHSGKIESSS AGAQIPGKVS
INVNSHVAAN RPLNSSVLVA SDSASEQQTP SSSPDIKVKL EGNVFLLDSD TKPDGSFSSN
EWQQVSKDSE FISAGCEQQQ DISVMTIPEH SDINDLEKSV WELEGMPQDT YTQQLHSQIQ
ESSLNQIQAQ SSDQLPLQSE LKEFEPSVSQ TNESYFPFDD ELTQDSIVEE LVLMEQQISM
NNSHSYGNCL GMTLQSQSVT PGAPMSSHAS STHFYHPIHS NGTPIHTPTP TPTPTPTPTP
TPTPTSEMIA GSQSLSRESP CSRLAQTTPV DSALGSSRHT PIGTPHSNCS SSVPPSPVEC
RNPFAFTPIS SSMAYHDASI ISSSPVKPMQ RPMATHPDKT KLEWMNNGYS GVSNSSVSGH
GILPSYQELV EDRFRKPHAF AVPGQSYQSQ SRHHDTHFGR LTPVSPVQHQ GATVNNTNKQ
EGFAVPAPLD NKGTNSSASS NFRCRSVSPA VHRQRNLSGS TLYPVSNIPR SNVTPFGSPV
TPEVHVFTNV HTDACANNIA QRSQSVPLTV MMQTAFPNAL QKQTNSKKIT NVLLSKLDSD
NDDAVRGLGM NNLPSNYTAR MNLTQILETS TVFPSANPQN MIDSSTSVYE FQTPSYLTKS
NSTDQISFSP GDNQAQSEIG EQQLDFNSTV KDLLSGDSLQ TNQQLVGQVA SDLTNTASDF
SSDIRLSSEL SGSINDLNTL DPNLLFDPGR QQGQDDEATL EELKNDPLFQ QICSESMSSM
TSSGFEWIES KDHPTVEMLG
//
