ID G1NC74_MELGA Unreviewed; 1029 AA.
AC G1NC74;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 3.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Contactin 4 {ECO:0000313|Ensembl:ENSMGAP00000010312.3};
GN Name=CNTN4 {ECO:0000313|Ensembl:ENSMGAP00000010312.3};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000010312.3, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000010312.3, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000010312.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with PTPRG. {ECO:0000256|ARBA:ARBA00038703}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. Contactin
CC family. {ECO:0000256|ARBA:ARBA00009812}.
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DR RefSeq; XP_010717053.1; XM_010718751.2.
DR AlphaFoldDB; G1NC74; -.
DR Ensembl; ENSMGAT00000011164.3; ENSMGAP00000010312.3; ENSMGAG00000009910.3.
DR GeneID; 100541983; -.
DR KEGG; mgp:100541983; -.
DR CTD; 152330; -.
DR GeneTree; ENSGT00940000155198; -.
DR HOGENOM; CLU_005756_0_0_1; -.
DR InParanoid; G1NC74; -.
DR TreeFam; TF351103; -.
DR Proteomes; UP000001645; Chromosome 14.
DR Bgee; ENSMGAG00000009910; Expressed in testis and 16 other cell types or tissues.
DR GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR CDD; cd00063; FN3; 4.
DR CDD; cd04969; Ig5_Contactin; 1.
DR CDD; cd05853; Ig6_Contactin-4; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR033007; CNTN4_Ig6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF18; CONTACTIN 4-RELATED; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 4.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 4.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000001645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1029
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5032750672"
FT DOMAIN 32..117
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 122..209
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 227..308
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 318..402
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 408..495
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 499..588
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 601..699
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 704..801
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 806..902
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 903..998
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 688..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1029 AA; 113280 MW; E30B9C3869CB0E00 CRC64;
MRLLWELLVL QSFMVCLADN NMLHGPVFLQ EPSSVIFPLD SEEKKVKLNC EVKGNPQPTI
GWKLNGTNID IGMDYRYSTV EGNLLINNPN KTQDTGTYQC VATNPFGRIV SREAKLQFAY
LENFKTRVRS TVSVRQGQGM VLLCGPPPHS GELTYAWIFN EYPSFVHQDN RRFVSQETGN
LYIAKVEASD VGNYTCVVTN TVTNSRVLGP PTPLILRNDG VMGEYEPKIE VQFPETVPSA
KGTAVKLECF ALGNPVPTIS WRRADGKQIP RKARRHRSNG LLEIPNFQQE DAGLYECVAE
NVRGKNVARG QLTFYAQPNW IQKISDVHAA IEENVFWECH ASGRPKPSYR WLKDGEPLLP
QGRVQIEQGS LTIRNVSLSD AGMYQCVAEN RHGTIFASAE LSVIAVGPDF SKTLLKKLTL
VKVGGEVIIE CKPKASPRPA YSWKKGKDIL RENERITVLD DGSLRIVNVT KSDTGSYTCV
ATNHFGTASS TGSLVVKDPT RVMVSPFSMD VTVGESIVLP CQVSHDHSLD IVFTWSFNGH
LIDFEKDGDH FEKVGGQDSA GDLMIRSIQL KHAGKYVCMV QTSVDKISAA ADLIVRGPPG
PPEDVTIDEI TDTTAQLSWR PGADNHSPIT MYVVQARTPF SVGWQAVSTV PEVIDGRTFT
ATVVGLNPWV EYEFRVVAAN LIGIGEPSRP SENRRTEEAL PEVTPANVSG GGGSKSELVI
TWETVPEELQ NGGGFGYVVA FRPFGTISWM QTVVASPDAS RYVFRNESLP PFSPYEVKVG
VYNNKGEGSF SPVTVVYSAE EEPTRAPITV LARSLSATDI EISWAPPREN QHKGRIQGYE
VRCWRHDEKE ETARKIRTVG NQTSAKVTNL QGNALYHLAV KAYNTAGTGP SSAMVNVTTK
KPPPSQPPGN IIWNSSDSKI ILNWDQVKAL DNESEVRGYK VLYRWNRQSS ASVIETNRTS
VELSLPFDED YIIEIKPFSD GGDGSSSEQI RIPKISNAYA RGGSSSTSNA CTLSAISTIM
ISLTARSSL
//
