ID G1PD20_MYOLU Unreviewed; 829 AA.
AC G1PD20;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000008339.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000008339.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000008339.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02051949; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02051950; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02051951; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PD20; -.
DR STRING; 59463.ENSMLUP00000008339; -.
DR Ensembl; ENSMLUT00000009151.2; ENSMLUP00000008339.2; ENSMLUG00000025304.1.
DR eggNOG; ENOG502RYEX; Eukaryota.
DR GeneTree; ENSGT01100000263478; -.
DR InParanoid; G1PD20; -.
DR TreeFam; TF336644; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:UniProt.
DR CDD; cd16843; IgC2_D1_D2_LILR_KIR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738:SF179; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 5; 1.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..829
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003417702"
FT TRANSMEM 641..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 125..197
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 224..311
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 321..393
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 670..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 90338 MW; 2E69E12A02B2AA8F CRC64;
MTSILSALLC LGLSLDQRTR VQAGTHPKPT IWAEPGPVIF WESPVTIWCQ GTPRAEEYRL
YKVGSTASLD QQKPLDSGDR AKFSITQMTM LDAGRYGCYY RSPSGQSEHS DTLELVVTVG
CYSKPSLSAL PSPVVTSGGN VTLQCGSGQG FHRFILTKEG DHRLSWTQDS EPQISGQFQA
LFTVGPVTPT QRWRFRCYGC YRNRPYVWSL PSDALELLVP GTFPKPTLWA EPGSLINWGS
SVTIWCQGTP EAEEYRLYKE GSTAWWYQQK TLDPGDRAKF SIRHMTDPDA GRYRCYYRSP
SGRSESSNPL ELVVTGSFSK PSLSAMPSPV VTAGGNVTLQ CGAGEGFYRF ILTKEGDHRF
SWALDSQPQT SGQNQALFPV GPVTPTQKWR FRCYGCYRNR PNVCSLPSDA LELLVPGESG
KPSLLSQQGP IVASGQSLTL QCHSDVGYDR FALHKEGRRD LPESLVLRPQ AGLSQAHFPL
GTVSSSHGGR YRCYGGYNLS SEWSAPSDPL DILVAGEEPV GPFLSVRPGP GVASGENVTL
LCQSQSWMNT FLLSKEGATD PPLGLRSKPG AQQFQAEFSI SPVTSAHGGT YRCYSSLSTS
SFLLSLPSEP LELLVSEPSG GPSPPPTGPT STAVLVPNWK VNILIGVLVA LVLLLSVLLL
LLRNRCQSKD RTSPLRGAHV QPPAGTTHPK GKDRGPKNSS SPSVDAHEEA LYASVKDPQP
GENVELDPQN RQDEGPQGVT YTQVNRSRPR LRQRMATSLS PLLGGLLDIR GRQAEEDRQM
DSQDAAGDIP ECVTYAQLNL LALNEKTTAA RFSPSDEPPD EHIVYASLS
//
