ID G1PS46_MYOLU Unreviewed; 981 AA.
AC G1PS46;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Retinoic acid induced 14 {ECO:0000313|Ensembl:ENSMLUP00000013977.2};
GN Name=RAI14 {ECO:0000313|Ensembl:ENSMLUP00000013977.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000013977.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000013977.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000013977.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAPE02020411; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02020412; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAPE02020413; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1PS46; -.
DR STRING; 59463.ENSMLUP00000013977; -.
DR Ensembl; ENSMLUT00000015340.2; ENSMLUP00000013977.2; ENSMLUG00000015329.2.
DR eggNOG; ENOG502QUEG; Eukaryota.
DR GeneTree; ENSGT00940000157400; -.
DR HOGENOM; CLU_005323_2_0_1; -.
DR InParanoid; G1PS46; -.
DR OMA; HTDCVQR; -.
DR TreeFam; TF331274; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0001650; C:fibrillar center; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24129; ANKYCORBIN; 1.
DR PANTHER; PTHR24129:SF0; ANKYCORBIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 7.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 52..84
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 85..117
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 118..150
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 806..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 693..727
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 247..272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..459
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..571
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 981 AA; 108782 MW; 5179B3BA966E0DC8 CRC64;
KKSLQSHFSR PETNEWNKND DRLLQAVENG DAEKVASLLG KKGASATKQD SEGKTAFHLA
ATKGHVECLR VMITHGVDVT AQDTAGHSAL HLAAKNSHHE CIRKLLQSKC PAENIDNSGK
TALHYAAAQG CLQAVQVLCE HKSPVNLKDL DGNIPLLLAV QNGHSEVCRF LLDHGADVNS
RDKNGRTALM VACEIGSCNV VEALIKKGAD LTLVDSLGHN ALHYSKLSEN AGIQSLLLSK
ISQDADLKTP TKPKQHDQVS KISSERSGTP KKRKAPPPPI SPAQLSDVSS PRSITSTPIS
GKESAFFAEP PFKAEISSIR ENKDRLSDST TGADSLLDIS SEADQPDILV LLQAKVASLT
LHNKELQDKL QAKTPKEAEA DLSFDSFHST HTDLAPSLEK PSETSPPNSR SPPPASAHPL
SKPPVGGGDV RIQQLQEVLQ DLQKRLESSE AERRQLQAEL QSRSPEPARL NNAEISENGS
DLSQKLKETQ SKYEEAMKEV LSVQKQMKLG LVSPESADSS SHLRELRVPE EEVRALKQDL
QKALEDSERN KEKVRELEEK LAEREKGTGS PPPAEEYEAM KSSYCSVIEN MNKEKAFLLE
KYQEAQEEIV QLKDTLKSQV AQEPGDDAGD MKEAMHRMID ELNKQVSELS QLYKEAQAEL
EDYRKRKSLE DVTAEYVHKA EHEKLMQVAG LSRAKAEEAL SEMKSQYSKA LQELAQLKQL
AEAQKENSVS IAEHLQVITT LRTAAKEMEA KLGGLQELLA SREVEVARLE KQLVEEKAAL
TEAMVPRAAY EKLQASLESE VSALASKLKD STKEKEKAQS EVAQVRSEAS QLKREKETLQ
TLLRSKEQEA GELLQKSQRA QEELAELRRH SESSSRLEED KDRKINEMSK EVTKLKEALN
SLSQLSYSAS SSKRQSQQLD GLQQQVKQLQ TQLTECKKQH QEVISVYRMH LLYAVQGQMD
EDVQKVLKQI LTMCKTQAQK K
//
