ID G1PS51_MYOLU Unreviewed; 770 AA.
AC G1PS51;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Semaphorin 3G {ECO:0000313|Ensembl:ENSMLUP00000013983.2};
GN Name=SEMA3G {ECO:0000313|Ensembl:ENSMLUP00000013983.2};
OS Myotis lucifugus (Little brown bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=59463 {ECO:0000313|Ensembl:ENSMLUP00000013983.2, ECO:0000313|Proteomes:UP000001074};
RN [1] {ECO:0000313|Ensembl:ENSMLUP00000013983.2, ECO:0000313|Proteomes:UP000001074}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSMLUP00000013983.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; AAPE02022326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006090876.1; XM_006090814.2.
DR AlphaFoldDB; G1PS51; -.
DR STRING; 59463.ENSMLUP00000013983; -.
DR Ensembl; ENSMLUT00000015347.2; ENSMLUP00000013983.2; ENSMLUG00000015339.2.
DR GeneID; 102422185; -.
DR KEGG; mlf:102422185; -.
DR CTD; 56920; -.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000157677; -.
DR HOGENOM; CLU_009051_5_0_1; -.
DR InParanoid; G1PS51; -.
DR OMA; DLQAMYL; -.
DR OrthoDB; 5342713at2759; -.
DR TreeFam; TF316102; -.
DR Proteomes; UP000001074; Unassembled WGS sequence.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR CDD; cd05871; Ig_Sema3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF20; SEMAPHORIN-3G; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001074};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..770
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003418957"
FT DOMAIN 30..517
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 583..665
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 770 AA; 85548 MW; 5031C73414926290 CRC64;
MASSAWAICC LLGSLLFHRG SPSPSASVPR LRLSYRELLS ANRSAIFLGP RGSLDLRVMY
LDEYRDRLFL GGRDAIYSLQ LDQPWADPRE VLWPPQPGQR EECVRKGRDP LVECANFVRV
LQPHNRTHLL ACGTGAFHPT CALIAVGHRG EHVLHLEAHS VESGRGRCPH EPSRPFASTF
VGGELYTGLT ADFLGREAMI FRSGGARPAL RSDSDQNLLH DPRFVMAARI ADNSDQNDDK
VYFFFSETVP SPDGGPGHVT VSRVGRVCVN DAGGQRVLVN KWSTFLKARL VCSVPGPGGA
ETHFDQLEDV FLLWPKAGKS LEVYALFSTV SAVFQGFAVC LYHMEDIWEV FKGPFAHQDG
PQHQWGPYGG KVPFPRPGVC PSKMTAQPGR PFGSTKDYPD EVLQFARAHP LMFRSVRPRQ
GRPVLVKTHL AQQLRQIVVD RVEAEDGTYD VIYLGTDSGS VLKVMALQSG DSAEPEEVVL
EELQVFKVPT AITEMEISVK RQMLYVGSRL GVARLKLHQC ETYGSACAEC CLARDPYCAW
DGASCTRYRP GTSKRRFRRQ DIRHGNPALQ CLGQSQEEKA AGPVATTTVF GTEHNSTFLE
CLPKSPQAAV RWFLQRPGGQ GPDQVKTDER VLQTEQGLLI RRLSRLDEGT YTCTTLEHGF
SQTVARLALE VIVAAQLNSL FHRGQRLEEP PARGSLASTP PKAWYKDILQ LIGFANLPRV
DEYCERMWCS SRSRGKQAKG KSWAGLELGK KVKSRVQAER NRTPREVEAT
//
