ID G1QMY3_NOMLE Unreviewed; 425 AA.
AC G1QMY3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=TRAF family member associated NFKB activator {ECO:0000313|Ensembl:ENSNLEP00000002299.1};
GN Name=TANK {ECO:0000313|Ensembl:ENSNLEP00000002299.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000002299.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000002299.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000002299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01031826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003266212.1; XM_003266164.2.
DR RefSeq; XP_003266213.1; XM_003266165.2.
DR AlphaFoldDB; G1QMY3; -.
DR STRING; 61853.ENSNLEP00000002299; -.
DR Ensembl; ENSNLET00000002425.2; ENSNLEP00000002299.1; ENSNLEG00000001877.3.
DR GeneTree; ENSGT00390000008712; -.
DR HOGENOM; CLU_053153_0_0_1; -.
DR InParanoid; G1QMY3; -.
DR OMA; IWQPQDN; -.
DR TreeFam; TF336453; -.
DR Proteomes; UP000001073; Chromosome 17.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:Ensembl.
DR GO; GO:0035800; F:deubiquitinase activator activity; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:Ensembl.
DR GO; GO:0140678; F:molecular function inhibitor activity; IEA:Ensembl.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
DR GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:InterPro.
DR GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR GO; GO:0006974; P:DNA damage response; IEA:Ensembl.
DR GO; GO:0043124; P:negative regulation of canonical NF-kappaB signal transduction; IEA:Ensembl.
DR GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR GO; GO:1903003; P:positive regulation of protein deubiquitination; IEA:Ensembl.
DR GO; GO:0032481; P:positive regulation of type I interferon production; IEA:Ensembl.
DR InterPro; IPR041641; CALCOCO1/2_Zn_UBZ1.
DR InterPro; IPR039669; TANK.
DR InterPro; IPR024581; TBD.
DR PANTHER; PTHR15249; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
DR PANTHER; PTHR15249:SF0; TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR; 1.
DR Pfam; PF12845; TBD; 1.
DR PROSITE; PS51905; ZF_UBZ1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01253}.
FT DOMAIN 393..420
FT /note="UBZ1-type"
FT /evidence="ECO:0000259|PROSITE:PS51905"
FT COILED 27..61
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 425 AA; 47872 MW; 5CAD866A01E52633 CRC64;
MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS
QLLLVKSTQD NSYGCVPLLE DSETRKNNLT VDQPHDKVIS GIAREKLPKV RRQEVSSPRK
ETSARSLGSP LLHERGNIEK TFWDLKEEFH RICMLAKAQK DHLSKLNIPD TATETQCSVP
IQCTDKTDKQ EALFKPQAKD DINRGAPSIT SVTPRGLCRD EEDTSFESLS KFNVKFPPMD
NDSTFLHSTP ERPGILSPAT SEAMCQEKFN MEFRDNPGNF VKTEETLFEI QGIDPIASAI
QNLKTTDKTK PSNLVNTCIR TTLDRAACLP PGDHNALYVN TFPLLDPSDA PFPSLDSPGK
AIRGPQQPIW KPFPNQDSDS VVLSGTDSEL HIPRVCEFCQ AVFPPSITSR GDFLRHLNSH
FNGET
//
