ID G1R9B1_NOMLE Unreviewed; 446 AA.
AC G1R9B1;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Regulator of G protein signaling 11 {ECO:0000313|Ensembl:ENSNLEP00000009800.2};
GN Name=RGS11 {ECO:0000313|Ensembl:ENSNLEP00000009800.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000009800.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000009800.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000009800.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01047897; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01047898; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01047899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003269150.2; XM_003269102.3.
DR AlphaFoldDB; G1R9B1; -.
DR STRING; 61853.ENSNLEP00000009800; -.
DR Ensembl; ENSNLET00000010271.2; ENSNLEP00000009800.2; ENSNLEG00000008018.2.
DR eggNOG; KOG3589; Eukaryota.
DR GeneTree; ENSGT00940000160198; -.
DR HOGENOM; CLU_025092_0_0_1; -.
DR InParanoid; G1R9B1; -.
DR OMA; WAFNFRE; -.
DR TreeFam; TF351956; -.
DR Proteomes; UP000001073; Chromosome 18.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0031681; F:G-protein beta-subunit binding; IEA:Ensembl.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR CDD; cd08740; RGS_RGS11; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF3; REGULATOR OF G-PROTEIN SIGNALING 11; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 11..86
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 282..397
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
SQ SEQUENCE 446 AA; 51011 MW; 939C82E5C01C709B CRC64;
MERVVVSMQD PDQGVKMRSQ RLLVTVIPHA VTGSDVVQWL AQKFCVSEEE ALHLGAVLVQ
HGYIYPLRDP RSLMLRPDET PYRFQTPYFW TSTLWPAAEL DYAIYLAKKN IRKRGTLVDY
EKECYDRLHK KINHAWDLVL MQAREQLRAA KQRRKGDRLV IACQEQTYWL VNRPPPGAPN
VLEQGPGRGS CAASRVHMTK SADFYKREIE YCRRALDRTR VKSSVCLEAY LSFCGQHGPH
DPLVSGCLPS NPWISDHDAY WVMNAPTVAA PTKLRVERWG FSFRELLEDP VGRAHFMDFL
GKEFSGENLS FWEACEELRY GAQAQVPTLV GAVYQQFLAP GAARWVNIDS RTMEQTLEGL
RQPHRYVLDD AQLHIYMLMK KDSYPRFLKS DMYKGLLAEA GIPLETKRRM FPFTWRPRHW
SPSPALLPTP VEPTVACGPG GGDGVA
//
