ID G1RDD6_NOMLE Unreviewed; 472 AA.
AC G1RDD6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Cation channel sperm associated 4 {ECO:0000313|Ensembl:ENSNLEP00000011235.1};
GN Name=CATSPER4 {ECO:0000313|Ensembl:ENSNLEP00000011235.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000011235.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000011235.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000011235.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01067250; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01067251; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003271694.1; XM_003271646.2.
DR AlphaFoldDB; G1RDD6; -.
DR Ensembl; ENSNLET00000011788.2; ENSNLEP00000011235.1; ENSNLEG00000009219.2.
DR GeneID; 100600401; -.
DR KEGG; nle:100600401; -.
DR CTD; 378807; -.
DR eggNOG; KOG2301; Eukaryota.
DR GeneTree; ENSGT00940000161879; -.
DR HOGENOM; CLU_042053_0_0_1; -.
DR OrthoDB; 2912377at2759; -.
DR TreeFam; TF343841; -.
DR Proteomes; UP000001073; Chromosome 24.
DR GO; GO:0036128; C:CatSper complex; IEA:InterPro.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR GO; GO:0030317; P:flagellated sperm motility; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR028744; CatSper4.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47077:SF1; CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4; 1.
DR PANTHER; PTHR47077; ION_TRANS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 93..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..315
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 419..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 472 AA; 54333 MW; 32FFD3FE9293D7E3 CRC64;
MRDNEKAWWQ QWTSHTGLVG WGGTQEDRMG FGGAVAALRG HPSPLHSTIH ESYGRPEEQV
LINRQEIMNK ADAWDMQEFI TRMYIKQLLR HPAFQLLLAL LLVMNAITIA LRTNSYLDQK
HYELFSTIDD IVLTILICEV LLGWLNDFWI FWKDGWNILN FIIVFVLLLR FFINEINIPS
INYTLRALRL VHVCMAVEPL ARIIRVILQS VPDMANIMVL ILFFMLVFSV FGVTLFGAFV
PKHFQNIQVA LYTLFICITQ DGWVDIYSDF QTEKREYAME IGGAIYFTIF ITIGAFIGIN
LFVIVVTTNL EQMMKAGEQG QQQRITFSET GAEEEEENDQ LPLVHCVVAR SKKSGLLQEP
LVGGPLSNLS ENTCDNFCLV LEAIQENLRQ YKEIRDELNM IVEEVRAIRF NQEQETEVLN
RRSSTSRSLE TTSSKDLRQM SQQQDLLSAL TNMEKVHDSS SQILLKKHKS SH
//
