ID G1RE75_NOMLE Unreviewed; 1429 AA.
AC G1RE75;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Ankyrin repeat domain containing 50 {ECO:0000313|Ensembl:ENSNLEP00000011525.1};
GN Name=ANKRD50 {ECO:0000313|Ensembl:ENSNLEP00000011525.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000011525.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000011525.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000011525.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01065253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012363085.1; XM_012507631.1.
DR STRING; 61853.ENSNLEP00000011525; -.
DR Ensembl; ENSNLET00000012090.2; ENSNLEP00000011525.1; ENSNLEG00000009475.2.
DR GeneID; 100595314; -.
DR KEGG; nle:100595314; -.
DR CTD; 57182; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000155116; -.
DR HOGENOM; CLU_002138_0_0_1; -.
DR InParanoid; G1RE75; -.
DR OMA; HSMSFTE; -.
DR OrthoDB; 5474600at2759; -.
DR TreeFam; TF323159; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR GO; GO:0032456; P:endocytic recycling; IEA:Ensembl.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 8.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24178:SF45; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 17.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 16.
DR PROSITE; PS50088; ANK_REPEAT; 17.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT REPEAT 544..576
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 577..609
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 610..642
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 643..675
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 676..708
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 709..746
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 747..779
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 780..812
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 813..845
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 846..878
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 879..911
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 912..944
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 945..977
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 978..1010
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1011..1043
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1044..1076
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1077..1103
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1108..1200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1217..1296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1160..1200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1429 AA; 155830 MW; A522562B9AE9DF2F CRC64;
MTNPWEEKVC KMAQTSLLQG KQFYCREWVF HKLQHCLQEK SNCCNSAVNA PSLVVNSGNN
ASGVSGKGAA WGVLLVGGPG SGKTALCTEL LWPSSPTSLQ RGLHRQALAF HFCKAQDSDT
LCVGGFIRGL VAQICRSGLL QGYEDKLRDP AVQSLLQPGE CERNPAEAFK RCVLLPLLGM
KPPQQSLYLL VDSVDEGCNI TEGEQTSTSL SGTVAALLAG HHEFFPPWLL LLCSARKQSK
AVTKMFTGFR KISLDDLRKA YIVKDVQQYI LHRLDQEEAL RQHLTKETAE MLNQLHIKSS
GCFLYLERVL DGVVENFIML REIRDIPGTL NGLYLWLCQR LFVRKQFAKV QPILNVILAA
CRPLTITELY HAVWTKNMSL TLEDFQRKLD VLSKLLVDGL GNTKILFHYS FAEWLLDVKH
CTQKYLCNAA EGHRMLAMSY TCQAKNLTPL EAQEFALHLI NSNLQLETAE LALWMIWNGT
PVRDSLSTLI PKEQEVLQLL VKAGAHVNSE DDRTSCIVRQ ALEREDSIRT LLDNGASVNQ
CDSNGRTLLA NAAYSGSLDV VNLLVSRGAD LEIEDAHGHT PLTLAARQGH TKVVNCLIGC
GANINHTDQD GWTALRSAAW GGHTEVVSAL LYAGVKVDCA DADSRTALRA AAWGGHEDIV
LNLLQHGAEV NKADNEGRTA LIAAAYMGHR EIVEHLLDHG AEVNHEDVDG RTALSVAALC
VPASKGHASV VSLLIDRGAE VDHCDKDGMT PLLVAAYEGH VDVVDLLLEG GADVDHTDNN
GRTPLLAAAS MGHASVVNTL LFWGAAVDSI DSEGRTVLSI ASAQGNVEVV RTLLDRGLDE
NHRDDAGWTP LHMAAFEGHR LICEALIEQG ARTNEIDNDG RIPFILASQE GHYDCVQILL
ENKSNIDQRG YDGRNALRVA ALEGHRDIVE LLFSHGADVN CKDADGRPTL YILALENQLT
MAEYFLENGA NVEASDAEGR TALHVSCWQG HMEMVQVLIA YHADVNAADN EKRSALQSAA
WQGHVKVVQL LIEHGAVVDH TCNQGATALC IAAQEGHIDA VQVLLEHGAD PNHADQFGRT
AMRVAAKNGH SQIIKLLEKY GASSLNGCSP SPVHTMEQKP LQSVSSKMQS LTIKSNSSGS
TGGGDMQPSL RGLPNGPAHA FSSPSESPDS TVDRQKSSLS NNSLKSSKNS SLRTTSSTAT
AQTVPIDSFH NLSFTEQIQQ HSLPRSRSRQ SIVSPSSTTQ SLGQSHNSPS SEFEWSQVKP
SLKSTKANKG GKSENSAKSG SAGKKAKQSN SSQPKVLEYE MTQFDRRGPI AKSGTAAPPK
QMPAESQCKI MIPSAQQEIG RSQQQFLIHQ QSGEQKKRNG IMTNPNYHLQ SNQVFLGRVS
VPRTMQDRGH QEVLEGYPSS ETELSLKQAL KLQIEGSDPS FNYKKETPL
//
