ID G1RLH6_NOMLE Unreviewed; 438 AA.
AC G1RLH6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Tripartite motif family like 2 {ECO:0000313|Ensembl:ENSNLEP00000014084.2};
GN Name=TRIML2 {ECO:0000313|Ensembl:ENSNLEP00000014084.2};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000014084.2, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000014084.2, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000014084.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01066359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01066360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1RLH6; -.
DR STRING; 61853.ENSNLEP00000014084; -.
DR Ensembl; ENSNLET00000014776.2; ENSNLEP00000014084.2; ENSNLEG00000011579.3.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000162029; -.
DR HOGENOM; CLU_013137_0_0_1; -.
DR InParanoid; G1RLH6; -.
DR OMA; EKKCGED; -.
DR TreeFam; TF338674; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF561; E3 UBIQUITIN-PROTEIN LIGASE TRIML2-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 14..55
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 231..427
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 55..137
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 438 AA; 49942 MW; 66E9D11732D77342 CRC64;
MSKRLSPRLQ HNITEDAYCE THLEPARLFC DVDQITLCSK CCQSQEHKHH MVCGIQEAAE
NYRKLFQEIL NTSREKLEAA KSILTDERER MAMIQEEEQN FKKMIESEYS MRLRLLNEEC
EQNLQRQQEC VSDLNLREAL PNQVINLATE LEEMFQEMLQ RLGHVGRENM KKLKESEARV
SKQICSLRKL IVELERKCGE GALALLKNAK YSLERSKSLL LEHLEPAHIT DLSLCHIRGL
SSMFRELQRH LTLDPETAHP CLALSEDLRT MRLRHGQQEG AGNPERLDFS AMVLAAESFT
SGRHYWEVDV EKATRWQVGI CHGSADTKGS TARASGEKVL LTGSVMGTEW TLWVFPPLKR
LFLEKKLDTV GVFLDYEHGQ ISFYNVTETS LIYNFSHCTF QGALRPVFSL CIPNGDASPD
SLTISPQRGP SCDAAVSP
//
