ID G1RP99_NOMLE Unreviewed; 583 AA.
AC G1RP99;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Protein disulfide isomerase like, testis expressed {ECO:0000313|Ensembl:ENSNLEP00000015063.1};
GN Name=PDILT {ECO:0000313|Ensembl:ENSNLEP00000015063.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000015063.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000015063.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000015063.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR EMBL; ADFV01197438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197439; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01197444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003261524.1; XM_003261476.1.
DR AlphaFoldDB; G1RP99; -.
DR STRING; 61853.ENSNLEP00000015063; -.
DR Ensembl; ENSNLET00000015818.2; ENSNLEP00000015063.1; ENSNLEG00000012398.2.
DR GeneID; 100602710; -.
DR KEGG; nle:100602710; -.
DR CTD; 204474; -.
DR eggNOG; KOG0191; Eukaryota.
DR GeneTree; ENSGT00940000160939; -.
DR HOGENOM; CLU_025879_1_1_1; -.
DR InParanoid; G1RP99; -.
DR OMA; APWSKKC; -.
DR OrthoDB; 5399045at2759; -.
DR TreeFam; TF106381; -.
DR Proteomes; UP000001073; Chromosome 2.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0003756; F:protein disulfide isomerase activity; IEA:Ensembl.
DR GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR CDD; cd02961; PDI_a_family; 1.
DR CDD; cd02995; PDI_a_PDI_a'_C; 1.
DR CDD; cd02982; PDI_b'_family; 1.
DR CDD; cd02981; PDI_b_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF58; PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS; 1.
DR Pfam; PF00085; Thioredoxin; 2.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 4.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..583
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003420189"
FT DOMAIN 368..494
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 549..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 66907 MW; 47CEAB42775923AE CRC64;
MDLLWMPLML VATCVSAVHS SPEVNAGVSS IHITKPVHIL EERNLLVLTP AGLTQMLNQT
RFLMVLFHNP SSKQSRNLAE ELGKAVEIMG KGKNGIGFGK VDITIEKELQ QEFGITKAPE
LKLFFEGNRS EPISCKGVVE STALVVWLRR QISQKAFLFN SSEQVAEFVI SRPVVIVGFF
QDLEEEVAEL FYDVIKDYPE LTFGVIMIGN VIGRFHVTLD SVLVFKKGKI VNRQKLINDS
TNKQELNRVI KQHLTDFVIQ YNTENKDLIY ELHIMSHMLL FVSKSSESYG IIIQHYKLAS
KEFQNKILFI LVDADEPRNG HVFEYFRVTE VDIPSVQILN LSSDARYKMP SDDITYENLK
KFGHSFLSKN AKKHQSSEEI PKYWDQGLVK QLVGKSFNIV VFDKEKDVFV MFYAPWSKKC
KMLFPLLEEL GRKYQNHSTI IIAKIDVTAN DIQLLYLDRY PFFRLFPSDS QQAVLYKGEH
TLKGFSDFLE SHIKTKIEDE DELLSVEQNE VTEEEVLAEE KEVPMMKKEL PEQQLPELQN
MTKYVSKLEE PAGKKKTSEE VVVVAKPKGP PTQKKKPKVK EEF
//
