ID G1RW75_NOMLE Unreviewed; 317 AA.
AC G1RW75;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=FCGR2A {ECO:0000313|Ensembl:ENSNLEP00000017502.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000017502.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000017502.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000017502.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01184117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004089886.1; XM_004089838.2.
DR AlphaFoldDB; G1RW75; -.
DR STRING; 61853.ENSNLEP00000017502; -.
DR Ensembl; ENSNLET00000018373.2; ENSNLEP00000017502.1; ENSNLEG00000014397.2.
DR eggNOG; ENOG502SVEW; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR HOGENOM; CLU_023383_1_2_1; -.
DR InParanoid; G1RW75; -.
DR OMA; LKCHGAH; -.
DR TreeFam; TF335097; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05752; Ig1_FcgammaR_like; 1.
DR CDD; cd05753; Ig2_FcgammaR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR PANTHER; PTHR11481:SF97; LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR II-A-RELATED; 1.
DR Pfam; PF13895; Ig_2; 2.
DR SMART; SM00409; IG; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW IgG-binding protein {ECO:0000256|ARBA:ARBA00022652};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..317
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003421847"
FT TRANSMEM 216..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..118
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 122..204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 317 AA; 35142 MW; 94C0AEBC513F2D71 CRC64;
MTMETLMSQN VRPCNLWLLQ PLTVLLLLAS ADSQAAAPPK AVLKLEPPWI NVLREDSVTL
TCRGAHSPES DSTQWFHNGN LIPTYTQPSY RFKANNNDSG EYRCQTGQTS LSDAVHLTVL
SEWLVLQTPH LEFQEGETIM LRCHSWKDRP LVKVTFFQNG KSKKFSRLDP NFSIPQANHS
HSGDYHCTGN IGYVLYSSKP VTITVQAPSV GSSSPMGIIV AVVTVTAVVA IVAAVVALIY
CRKKRISANS TDSVKAAQFE LPGRQMIAIR KRQLEETNND YEIADGGYMT LNPRAPTDDD
KNIYLTLPPN DHVNSNN
//
