ID G1SPU3_RABIT Unreviewed; 440 AA.
AC G1SPU3;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=AFG1 like ATPase {ECO:0000313|Ensembl:ENSOCUP00000005080.4};
GN Name=AFG1L {ECO:0000313|Ensembl:ENSOCUP00000005080.4};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000005080.4, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000005080.4, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000005080.4,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000005080.4}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000005080.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AFG1 ATPase family.
CC {ECO:0000256|ARBA:ARBA00010322}.
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DR EMBL; AAGW02029516; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029517; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029519; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029520; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAGW02029523; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1SPU3; -.
DR PaxDb; 9986-ENSOCUP00000005080; -.
DR Ensembl; ENSOCUT00000005863.4; ENSOCUP00000005080.4; ENSOCUG00000005862.4.
DR eggNOG; KOG2383; Eukaryota.
DR GeneTree; ENSGT00390000013227; -.
DR HOGENOM; CLU_008681_0_1_1; -.
DR TreeFam; TF314551; -.
DR Proteomes; UP000001811; Chromosome 12.
DR Bgee; ENSOCUG00000005862; Expressed in heart and 15 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR005654; ATPase_AFG1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; NF040713; ZapE; 1.
DR PANTHER; PTHR12169:SF6; AFG1-LIKE ATPASE; 1.
DR PANTHER; PTHR12169; ATPASE N2B; 1.
DR Pfam; PF03969; AFG1_ATPase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811}.
SQ SEQUENCE 440 AA; 50165 MW; FF81122FC1E2C219 CRC64;
MAASWSPLVT LRSLTQCRLR GKCVGFGAWV AALAPPATAP GKPLWKASLG PIYSTVRNTL
CMIMFNSVHG RDLRFVLNLQ LFSRSKPPRG LYVYGDVGTG KTMVMDMFYA YVEMKRKKRV
HFHGFMLDVH KRIHRLKQSL PKRKPGFMAK SYDPIAPIAE EISQEACLLC FDEFQVTDIA
DAMILKQLFE NLFKNGVVVV ATSNRPPEDL YKNGLQRANF VPFIAVLKEY CNTVQLDSGV
DYRKRDLPSA GKLYYLTSEA DVEAVVDKLF DELAQKQNDL TRPRILKVQG RELWLNKACG
TIADCTFEEL CERPLGASDY LELAKNFDTV FLRNIPQFTL AKRTQARRFI TLIDNFYDFK
VRIICSASAP IASLFLHQHH DSELEQSRIL MDDLGLSQDS AEGLSMFTGE EEVFAFQRTI
SRLTEMQTEQ YWNEGDRSKK
//
