ID G1U5D6_RABIT Unreviewed; 586 AA.
AC G1U5D6;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Tripartite motif containing 29 {ECO:0000313|Ensembl:ENSOCUP00000024615.2};
GN Name=TRIM29 {ECO:0000313|Ensembl:ENSOCUP00000024615.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000024615.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000024615.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000024615.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000024615.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000024615.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02009496; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1U5D6; -.
DR PaxDb; 9986-ENSOCUP00000024615; -.
DR Ensembl; ENSOCUT00000028494.2; ENSOCUP00000024615.2; ENSOCUG00000021297.3.
DR eggNOG; ENOG502QWDV; Eukaryota.
DR GeneTree; ENSGT00940000161416; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000001811; Chromosome 1.
DR Bgee; ENSOCUG00000021297; Expressed in autopod skin and 8 other cell types or tissues.
DR ExpressionAtlas; G1U5D6; baseline.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19840; Bbox1_TRIM29; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF7; TRIPARTITE MOTIF-CONTAINING PROTEIN 29; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 219..259
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 478..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 267..337
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 65371 MW; D2209B3187071A5B CRC64;
MEAADASRSN GSTPEARDSR SPQGPSGGLE NGTKADGKDA KTTNGHSGEA AEGKGLGSAL
KAAEGKSALF SSSEWRRIIQ FVDSVDDKGS NYFSMDSAEG RRSPYAGLQL GAAKKPPVTF
AEKGELRKSI FSEARKPAVS IMEPGEGRRN SSPRADAGLL LRSKAGSEEV LCDSCIGNKQ
KAVKSCLVCQ ASFCELHLKP HLEGAAFRDH QLLEPIRDFE ARKCPLHGKT MELFCQTDQT
CICYLCMFQE HKNHSTVTVE EAKAEKETEL SLQKEQLQLK IIEIEDEAEK WQKEKDRIKS
FTTNEKAILE QNFRELVRDL EKQKEEVRAA LEQREQDAVD QVKVIVDALD ERAKVLHEDK
QIREQLHSIS DSVLFLQEFG ALMSNYSLPP PLPTYHVLLE GEGLGQSLGN FKDDLLNVCM
RHVEKMCKAD LSRNFIERNH MENGGDHRYM NNYTNSYTSE WSTPDTMKRY SMYLTPKGGA
RTSYQPGSPS RLSKETNQKN FSNLYGTKGN YTSRVWEYSS SVQSSDDLPA VQGSSSFSLK
GYPSLVRSQV PKAQPQTWRS GKQTLLSHYR PFYVNKGNGM GSNEAP
//
