ID G1U9L2_RABIT Unreviewed; 423 AA.
AC G1U9L2;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=WD repeat domain 88 {ECO:0000313|Ensembl:ENSOCUP00000026133.2};
GN Name=WDR88 {ECO:0000313|Ensembl:ENSOCUP00000026133.2};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|Ensembl:ENSOCUP00000026133.2, ECO:0000313|Proteomes:UP000001811};
RN [1] {ECO:0000313|Ensembl:ENSOCUP00000026133.2, ECO:0000313|Proteomes:UP000001811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thorbecke inbred {ECO:0000313|Ensembl:ENSOCUP00000026133.2,
RC ECO:0000313|Proteomes:UP000001811};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSOCUP00000026133.2}
RP IDENTIFICATION.
RC STRAIN=Thorbecke {ECO:0000313|Ensembl:ENSOCUP00000026133.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAGW02068715; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G1U9L2; -.
DR SMR; G1U9L2; -.
DR STRING; 9986.ENSOCUP00000026133; -.
DR PaxDb; 9986-ENSOCUP00000026133; -.
DR Ensembl; ENSOCUT00000033020.2; ENSOCUP00000026133.2; ENSOCUG00000029028.2.
DR eggNOG; KOG0266; Eukaryota.
DR GeneTree; ENSGT00940000162291; -.
DR HOGENOM; CLU_000288_57_3_1; -.
DR InParanoid; G1U9L2; -.
DR TreeFam; TF300039; -.
DR Proteomes; UP000001811; Chromosome 5.
DR Bgee; ENSOCUG00000029028; Expressed in testis and 4 other cell types or tissues.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR45048; -; 1.
DR PANTHER; PTHR45048:SF1; WD REPEAT-CONTAINING PROTEIN 88; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00564; PQQ; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001811};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 97..138
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 140..181
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 225..266
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 268..309
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 316..357
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 358..399
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 47603 MW; 98A0D25A263006A4 CRC64;
WALRRPGCRE TMGEDWKKPL GPDSSHRRMP LVTLVRTFGG FKMSTPEARQ DRLLATLDPL
ALGKSSLPSP PQSDMYYMQE EVWGDQEPLS KIPFKILSGH DHVVSSCHFC VDDTKLLSGS
YDCTVKLWNA FNGAVEREFE HGPEAPVVEC SVSADSRRVI AASYDKTVRA WDLETGKMLW
KISHDNFIVS CKLSPDGKYV VSGLDVDRGI CITDMENVTT VAHVKDHHQR SLTACCFDPD
SQKVASVSLD RTIKIWDVTS QATLLTIPKA HANAISNCCF TFSGHFLCTC SWDKSLKIWN
VHTGEFRNSG ACVTLMKGHE GSVSSCFFAR DSSFLISGGF DKTVAIWDIT EGYRKLALKG
HKDWVMDVAI SSNKKWILSA SKDRTMRIWN IEEIDEIPLV IKQKKARGLK VQQEKKETYL
KLW
//
