ID G1UB03_LACJO Unreviewed; 384 AA.
AC G1UB03;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Cysteine desulfurase NifS {ECO:0000313|EMBL:AAS08806.1};
GN OrderedLocusNames=LJ_0984 {ECO:0000313|EMBL:AAS08806.1};
OS Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=257314 {ECO:0000313|EMBL:AAS08806.1, ECO:0000313|Proteomes:UP000000581};
RN [1] {ECO:0000313|EMBL:AAS08806.1, ECO:0000313|Proteomes:UP000000581}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNCM I-1225 / La1 / NCC 533
RC {ECO:0000313|Proteomes:UP000000581};
RX PubMed=14983040; DOI=10.1073/pnas.0307327101;
RA Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C.,
RA Pittet A.-C., Zwahlen M.-C., Rouvet M., Altermann E., Barrangou R.,
RA Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.;
RT "The genome sequence of the probiotic intestinal bacterium Lactobacillus
RT johnsonii NCC 533.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC aminotransferase family. NifS/IscS subfamily.
CC {ECO:0000256|ARBA:ARBA00006490}.
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DR EMBL; AE017198; AAS08806.1; -; Genomic_DNA.
DR RefSeq; WP_011161850.1; NC_005362.1.
DR AlphaFoldDB; G1UB03; -.
DR GeneID; 83570579; -.
DR KEGG; ljo:LJ_0984; -.
DR PATRIC; fig|257314.6.peg.844; -.
DR eggNOG; COG1104; Bacteria.
DR HOGENOM; CLU_003433_0_0_9; -.
DR Proteomes; UP000000581; Chromosome.
DR GO; GO:0031071; F:cysteine desulfurase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.260.50; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000192; Aminotrans_V_dom.
DR InterPro; IPR016454; Cysteine_dSase.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11601:SF34; CYSTEINE DESULFURASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11601; CYSTEINE DESULFURYLASE FAMILY MEMBER; 1.
DR Pfam; PF00266; Aminotran_5; 1.
DR PIRSF; PIRSF005572; NifS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 6..371
FT /note="Aminotransferase class V"
FT /evidence="ECO:0000259|Pfam:PF00266"
SQ SEQUENCE 384 AA; 42520 MW; 47DD020454D5024F CRC64;
MTRKNVYLDN AATTPMDPKV IEKISSEMAD DFGNASSQHA FGRKARHVVE TARHQLAETI
NAQDKEIIFT SGGSESNNTA IFGTVRARKD IGKKIITTKI EHPSVLNPMK RLAQEGYEIV
YLDVDETGHI NLDDLKRELT PDTILVSIMA VNNEVGSIMP LKEIGELVKD SNAYFHVDDV
QGFGNIEIDV KEMNIDLLST SAHKVNGPKF LGFLYEKNGL KVSNLLLGGE QETKRRPGTE
NVPGIAGFGI AAQELNEMDK QKLQEKYQNF QKIILDELDK NQIDYEVNGT LEGKVSHHVL
NLWLKGVGTY SALTNLDLSG YAVSGGSACT AGSLTPSHVL QAMYGEDSPR IEESIRISFG
RFNTEEEIQE FAADLVKMCK RLDK
//
