ID   G1UGF1_ECOLX            Unreviewed;       366 AA.
AC   G1UGF1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Perosamine synthetase {ECO:0000313|EMBL:BAK69188.1};
GN   Name=rfbE {ECO:0000313|EMBL:BAK69188.1};
OS   Escherichia coli O157:H43.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=626531 {ECO:0000313|EMBL:BAK69188.1};
RN   [1] {ECO:0000313|EMBL:BAK69188.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PV00-24 {ECO:0000313|EMBL:BAK69188.1};
RA   Iguchi A., Hayashi T., Ooka T., Ogura Y.;
RT   "Genomic Comparison of the O-antigen Biosynthesis Gene Clusters of
RT   Escherichia coli O157 strains.";
RL   Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
CC       {ECO:0000256|ARBA:ARBA00037999, ECO:0000256|RuleBase:RU004508}.
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DR   EMBL; AB602253; BAK69188.1; -; Genomic_DNA.
DR   AlphaFoldDB; G1UGF1; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   CDD; cd00616; AHBA_syn; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000653; DegT/StrS_aminotransferase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR30244:SF43; PYRIDOXAL PHOSPHATE-DEPENDENT AMINOTRANSFERASE EPSN-RELATED; 1.
DR   PANTHER; PTHR30244; TRANSAMINASE; 1.
DR   Pfam; PF01041; DegT_DnrJ_EryC1; 1.
DR   PIRSF; PIRSF000390; PLP_StrS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR000390-2}.
FT   ACT_SITE        185
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000390-1"
FT   MOD_RES         185
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000390-2"
SQ   SEQUENCE   366 AA;  41814 MW;  6026BD28811805D9 CRC64;
     MKMKYIPVYQ PSLTGKEKEY VNECLDSTWI SSKGNYIQKF ENKFAEQNHV QYATTVSNGT
     VALHLALLAL GISEGDEVIV PTLTYIASVN AIKYTGATPI FVDSDNETWQ MSVSDIEQKI
     TNKTKAIMCV HLYGHPCDME QIVELAKSRN LFVIEDCAEA FGSKYKGKYV GTFGDISTFS
     FFGNKTITTG EGGMVVTNDK TLYDRCLHFK GQGLAVHRQY WHDVIGYNYR MTNICAAIGL
     AQLEQADDFI SRKREIADIY KKNINSLVQV HKESKDVFHT YWMVSILTRT AEEREELRNH
     LADKLIETRP VFYPVHTMPM YSEKYQKHPI AEDLGWRGIN LPSFPSLSNE QVIYICESIN
     EFYSDK
//