ID G1WIH7_9ACTN Unreviewed; 963 AA.
AC G1WIH7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Penicillin-binding protein transpeptidase domain-containing protein {ECO:0000259|Pfam:PF00905};
GN ORFNames=HMPREF9452_01140 {ECO:0000313|EMBL:EGX71013.1};
OS Collinsella tanakaei YIT 12063.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC Coriobacteriaceae; Collinsella.
OX NCBI_TaxID=742742 {ECO:0000313|EMBL:EGX71013.1, ECO:0000313|Proteomes:UP000004830};
RN [1] {ECO:0000313|EMBL:EGX71013.1, ECO:0000313|Proteomes:UP000004830}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12063 {ECO:0000313|EMBL:EGX71013.1,
RC ECO:0000313|Proteomes:UP000004830};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Collinsella tanakaei YIT 12063.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX71013.1}.
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DR EMBL; ADLS01000013; EGX71013.1; -; Genomic_DNA.
DR RefSeq; WP_009141175.1; NZ_JH126469.1.
DR AlphaFoldDB; G1WIH7; -.
DR STRING; 742742.HMPREF9452_01140; -.
DR GeneID; 62758867; -.
DR PATRIC; fig|742742.3.peg.1109; -.
DR eggNOG; COG0768; Bacteria.
DR eggNOG; COG0772; Bacteria.
DR HOGENOM; CLU_012814_1_0_11; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000004830; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001182; FtsW/RodA.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF01098; FTSW_RODA_SPOVE; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004830};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 645..948
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 963 AA; 100388 MW; 742376EB25182CA1 CRC64;
MSSRRNTELF LLISAAFPVV LLYAMYVITT GTALTFQTLA VPLGLFAAFA AAHIAVRILA
PGADPAILPV VFLLSGVGIT FVTRVKPELA MNQLIILFAS IVLMVITLAL VKNLDVVKKY
KYSLGAIGIL LLLLPIFIGT EIYGSKLWIT IGGFSIQPGE FAKVFIVLFL AGYLAENREL
LSISNHEVLG FKVPRLKLLL PLFVVWGICM LIVAFERDLG SAVLFYTIFL LMLYVATGRI
SYVVIGFVLL AVGGFGAYKV MSHVQTRFQI WLDPFADPSG DGYQLVQSLF SLADGGLVGT
GIGKGMPTLI PIVESDFIFS AIGEEMGLLG GAAVLFLFML FAVRGLTTAA RAKSDLAAFC
ASGLTAAISF QAFLIVGGVT RLIPLTGVTL PFMSQGGSSL LSSFIIVALL LRAGDEATGR
EAELSGTGIM AAQDVPVPGG VSAAGTRVYG GNASAAGLTG SAGGSHARPG SRLRRRLLDT
PESGVLGRVA LAKRLTVAVF AFTALFAILV GNLTYIQVFK AKDYQNMSIN NHSIARAAYV
KRGSIITSDG VTLAESIQNE DGTYSRSHPN GNLAANVVGY YSTRYGTAGV ESTMNETLTG
SKDYSSWMNA VNSLAGISQP GNSVKLTIDS RIQSAAEQAL SGMSGAIVVL DPRTGAVLAS
ATAPSYDNND VEASISATEE SGVSMYDRAT QALYTPGSTF KVITLAAALD TGASSLQETY
SAPSSMEIGN ADVTNYENAN FGTISLRRAF AVSSNVVFGQ VANQVGATSL VQHANAFGYG
QPLGLDFSTA ASIMPDPSLM TEWELAWAGA GQPVGQGHTA GPQTTPMQNA VMAAAIANGG
IAMNPYVVAQ TLSPEGTVIK STQPRSLGQA VSSSTAQQVK EAMLDVVEEG SGGAAAVAGV
KVAGKTGTAE TGTHVNSVFV GFAPYDTPTV AISVMLENYD VHGVKATYVA SQVLSAALSA
QGL
//
