ID G1X0C7_ARTOA Unreviewed; 774 AA.
AC G1X0C7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=AOL_s00006g328 {ECO:0000313|EMBL:EGX53462.1};
OS Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)
OS (Nematode-trapping fungus) (Didymozoophaga oligospora).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Orbilia; Orbilia oligospora.
OX NCBI_TaxID=756982 {ECO:0000313|EMBL:EGX53462.1, ECO:0000313|Proteomes:UP000008784};
RN [1] {ECO:0000313|EMBL:EGX53462.1, ECO:0000313|Proteomes:UP000008784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24927 / CBS 115.81 / DSM 1491
RC {ECO:0000313|Proteomes:UP000008784};
RX PubMed=21909256; DOI=10.1371/journal.ppat.1002179;
RA Yang J., Wang L., Ji X., Feng Y., Li X., Zou C., Xu J., Ren Y., Mi Q.,
RA Wu J., Liu S., Liu Y., Huang X., Wang H., Niu X., Li J., Liang L., Luo Y.,
RA Ji K., Zhou W., Yu Z., Li G., Liu Y., Li L., Qiao M., Feng L., Zhang K.-Q.;
RT "Genomic and proteomic analyses of the fungus Arthrobotrys oligospora
RT provide insights into nematode-trap formation.";
RL PLoS Pathog. 7:E1002179-E1002179(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX53462.1}.
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DR EMBL; ADOT01000012; EGX53462.1; -; Genomic_DNA.
DR RefSeq; XP_011117939.1; XM_011119637.1.
DR AlphaFoldDB; G1X0C7; -.
DR STRING; 756982.G1X0C7; -.
DR GeneID; 22888851; -.
DR eggNOG; KOG1979; Eukaryota.
DR HOGENOM; CLU_004131_2_0_1; -.
DR InParanoid; G1X0C7; -.
DR OMA; ANYHVKK; -.
DR OrthoDB; 5475669at2759; -.
DR Proteomes; UP000008784; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008784}.
FT DOMAIN 258..377
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 86056 MW; B7DBA69A132DC140 CRC64;
MADDMDISAD TPEQPEVMAS NDDPRGTKRK ATDELLGNAP RRIKALSQTV VNKIAAGEII
VAPVHALKEL LENAVDAGST SIEVVVKDGG LKMLQITDNG SGINKDDMGI LCERFTTSKL
KTFEDLASIG TYGFRGEALA SISHIAHLSV TTRTKDSDCA WRALYSDGKL IPPKPGGSAE
PKAVAGRQGT QITVEDLFYN VPSRRRAFRN TNEEYSKVLD MVGKYAIHCD GIAFSCKKHG
ESSMGVAIQS TAKTIDRVRQ IYGNAVANEL IPFKIEDQKL GFKAKGLITN ANYSIKKTTM
LLFINHRCVE STAIRKSLES VYSAFLPKGG HPYIYATIEI EPHRIDVNVH PTKREVNFLH
EDEIIERISD AVQEKLAAVD TSRSFMTQTV LPGAGIPSSS ALPPTTQASS SRGTAANTPA
KPSQTPKRPY ENEMVRTDAR VRKITSMLPP ATPSSASGDI FRSLKHNDAP NGEYEDDSQP
NYEVIDTNRR VIKLASIRTL KTEVRDQAHE GLIELFGNHT WVGVVDEWRR LAAVQNGIKL
YLVDYGAVCF EFFYQLALTD FGNFGQMRLQ EPLSIRDLMD IAVELEKNAE IEETGEIQSD
WEGVAAQVTE TVFEKREMMS EYFSLIINDE GEIESIPLLL KGYTPNLAKL PTFLLRLGPR
VNWEDELECF DCIIRELAIF YVPESVPRPV QFTGATQATE GEDSEMTGTS DSVPAEIREQ
IEVYETRRKE IGIALERVLF PEFRKRLLPS KKLLKGITEV ANLKGLYRIF ERSC
//
