ID G1X4D1_ARTOA Unreviewed; 516 AA.
AC G1X4D1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Polyadenylation factor subunit 2 {ECO:0000256|ARBA:ARBA00026154, ECO:0000256|RuleBase:RU369034};
GN ORFNames=AOL_s00043g555 {ECO:0000313|EMBL:EGX51821.1};
OS Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)
OS (Nematode-trapping fungus) (Didymozoophaga oligospora).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Orbilia; Orbilia oligospora.
OX NCBI_TaxID=756982 {ECO:0000313|EMBL:EGX51821.1, ECO:0000313|Proteomes:UP000008784};
RN [1] {ECO:0000313|EMBL:EGX51821.1, ECO:0000313|Proteomes:UP000008784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24927 / CBS 115.81 / DSM 1491
RC {ECO:0000313|Proteomes:UP000008784};
RX PubMed=21909256; DOI=10.1371/journal.ppat.1002179;
RA Yang J., Wang L., Ji X., Feng Y., Li X., Zou C., Xu J., Ren Y., Mi Q.,
RA Wu J., Liu S., Liu Y., Huang X., Wang H., Niu X., Li J., Liang L., Luo Y.,
RA Ji K., Zhou W., Yu Z., Li G., Liu Y., Li L., Qiao M., Feng L., Zhang K.-Q.;
RT "Genomic and proteomic analyses of the fungus Arthrobotrys oligospora
RT provide insights into nematode-trap formation.";
RL PLoS Pathog. 7:E1002179-E1002179(2011).
CC -!- FUNCTION: Required for 3'-end cleavage and polyadenylation of pre-
CC mRNAs. Also involved in chromosome segregation where it has a role in
CC chromosome attachment to the mitotic spindle.
CC {ECO:0000256|ARBA:ARBA00025498}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369034}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX51821.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADOT01000060; EGX51821.1; -; Genomic_DNA.
DR RefSeq; XP_011119343.1; XM_011121041.1.
DR AlphaFoldDB; G1X4D1; -.
DR STRING; 756982.G1X4D1; -.
DR GeneID; 22890280; -.
DR eggNOG; KOG0284; Eukaryota.
DR HOGENOM; CLU_000288_77_1_1; -.
DR InParanoid; G1X4D1; -.
DR OMA; YGSSMVQ; -.
DR OrthoDB; 5487329at2759; -.
DR Proteomes; UP000008784; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:UniProtKB-UniRule.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR045245; Pfs2-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22836:SF0; PRE-MRNA 3' END PROCESSING PROTEIN WDR33; 1.
DR PANTHER; PTHR22836; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|RuleBase:RU369034};
KW Nucleus {ECO:0000256|RuleBase:RU369034};
KW Reference proteome {ECO:0000313|Proteomes:UP000008784};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 89..121
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 131..163
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 172..213
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 214..255
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 256..298
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 299..329
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 354..385
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..490
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 57209 MW; 855BA3CC2973F927 CRC64;
MAQKRGFEPS GNAGDGGPPR KFTHRRPVTD YGSSLARWIF DRRLDFRPHC QAGSSFAEEG
TYLKELLPSI SATTNVVAQI PIRHIHASLN KIKHPINMVK WTPEGRRLLT GSSSGEFTLW
NGMGFNFETI MQAHDSAIRA LEYSHGADWL LSGDQDGIVK YWQTNFNNVK VLQAHDSPVR
DVSFCPTDAK FVTASDDGSL KIWNFGEGEE ERILSGHGWD VKSAHWHPYK GLIASGSKDH
LVKLWDPRSA RCLTTLHGHK NTVSRVRFQP SQGHLLATSG RDMTIRIFDL RTMKDLCILR
DHEKEVSSLA WHPTIPSLLS SGSLDGSVRH FVLDELSAST GGSVSVVRAA VSVPHAHENA
VWSMEYHPLG HILCTGSNDR STRFWGRPRV GEIESFSERQ YTGEGAYESR NDNKGKKKHQ
PKEEEEEADD DDYLIDQQMP VPGAGPTPVH PMGNMPPFPP GMDLGGALPL PGLPGLPGLG
FPPPPPGFDP TLAVLAAMQQ QQQQQQHSQQ NQMPRQ
//
