ID G2J9G7_9BURK Unreviewed; 903 AA.
AC G2J9G7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982, ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN ECO:0000313|EMBL:CCD29414.1};
GN ORFNames=CAGGBEG34_230056 {ECO:0000313|EMBL:CCD29414.1};
OS Candidatus Glomeribacter gigasporarum BEG34.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Glomeribacter.
OX NCBI_TaxID=1070319 {ECO:0000313|EMBL:CCD29414.1, ECO:0000313|Proteomes:UP000054051};
RN [1] {ECO:0000313|EMBL:CCD29414.1, ECO:0000313|Proteomes:UP000054051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BEG34 {ECO:0000313|EMBL:CCD29414.1,
RC ECO:0000313|Proteomes:UP000054051};
RA Ghignone S., Salvioli A., Anca I., Lumini E., Ortu G., Petiti L.,
RA Cruveiller S., Bianciotto V., Piffanelli P., Lanfranco L., Bonfante P.;
RT "The genome of the obligate endobacterium of an arbuscular mycorrhizal
RT fungus reveals an interphylum network of nutritional interactions.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647,
CC ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCD29414.1}.
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DR EMBL; CAFB01000040; CCD29414.1; -; Genomic_DNA.
DR RefSeq; WP_006682605.1; NZ_CAFB01000040.1.
DR AlphaFoldDB; G2J9G7; -.
DR STRING; 1070319.CAGGBEG34_230056; -.
DR eggNOG; COG0249; Bacteria.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000054051; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000054051}.
FT DOMAIN 747..763
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 673..680
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 903 AA; 98959 MW; 1DC16F497A085DD8 CRC64;
MDEKPRPARS ARRATDIAAH TPMMQQYLKI KSGYPEMLLL YRMGDFYELF YEDAEKAARL
LDLTLTQRGA SNGQPIRMAG VPHHALDAYL ARLVKLGESV AICEQTGDPN ASKGPVERKV
VRVVTPGTLT DAALLADRQD AYLLALCTVQ NRSGGRAPLE HFSVRLHKEQ ARRQYAQYGE
REATQSKPLK NALIGLAWLN LASGALRLAE MAADEAPAAL ERIRPAEILL ADADSGPDAM
EPPAGPGAVT RIPPWHFEID SGRARLCEQL GVTHLEGFGA HHLSAACGAA GAVLWYAVNT
QGQPLRHIGS LQVESETQYI GLDPATRRNL ELTETLRGAE SPTLLSRLDR CCTSMGSRLL
RHWLHHAPRD ARIAQRRQQA IGAWLQAPSG ARALDTLRQS LRQIADIERI TGRLALLTAR
PRDLAHLRDT LIQLPCVRAH LADDALPAEL LQGIEAALHA PDDCLALLER AIAAEPAALI
RDGGVIAHGY DAELDALRAL SENCGQFLNE LEARERARTG IANLRVEYNK VHGFYIEVTR
GQTDKVPDDY RRRQTLKNAE RYITPELKAF EDKALSASGR ALAREKALYE ALLQTLSAYI
ADCQRIAQAL AQLDVLAAFA ERARLLHWAA PEFGGEGIEI EQGRHPVVET QIDPFVPNDC
RLSAQRKLLL ITGPNMGGKS TFMRQTALIV LMAYIGSYVP ARRARFGPVD RIFTRIGAQD
DLAGGRSTFM VEMTEAAAIL NGATPSSLVL IDEIGRGTST FDGLALAWAI AHRLLAHNRC
YTLFATHYFE LTRLADECAQ AANAHLSAVE HAQGLVFLHA VQDGPASQSY GLQVAQLAGV
PRPVIEAARA HLAHLSGDLP RARMETHPAL EKLRALDPKN MRARDALNAL FELHALAMAH
WNG
//
