ID   G2PXV2_9FIRM            Unreviewed;       625 AA.
AC   G2PXV2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Sialate O-acetylesterase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=Calla_1329 {ECO:0000313|EMBL:AEM73948.1};
OS   Caldicellulosiruptor acetigenus 6A.
OC   Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC   Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX   NCBI_TaxID=632516 {ECO:0000313|EMBL:AEM73948.1, ECO:0000313|Proteomes:UP000009257};
RN   [1] {ECO:0000313|EMBL:AEM73948.1, ECO:0000313|Proteomes:UP000009257}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=6A {ECO:0000313|EMBL:AEM73948.1,
RC   ECO:0000313|Proteomes:UP000009257};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Blumer-Schuette S.E.,
RA   Kelly R.M., Woyke T.;
RT   "Complete sequence of Caldicellulosiruptor lactoaceticus 6A.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; CP003001; AEM73948.1; -; Genomic_DNA.
DR   RefSeq; WP_014042645.1; NC_015949.1.
DR   AlphaFoldDB; G2PXV2; -.
DR   KEGG; clc:Calla_1329; -.
DR   HOGENOM; CLU_015150_2_0_9; -.
DR   Proteomes; UP000009257; Chromosome.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0001681; F:sialate O-acetylesterase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR005181; SASA.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   InterPro; IPR039329; SIAE.
DR   PANTHER; PTHR22901; SIALATE O-ACETYLESTERASE; 1.
DR   PANTHER; PTHR22901:SF0; SIALATE O-ACETYLESTERASE; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   Pfam; PF03629; SASA; 2.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          85..190
FT                   /note="Sialate O-acetylesterase"
FT                   /evidence="ECO:0000259|Pfam:PF03629"
FT   DOMAIN          249..361
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          405..509
FT                   /note="Sialate O-acetylesterase"
FT                   /evidence="ECO:0000259|Pfam:PF03629"
SQ   SEQUENCE   625 AA;  70717 MW;  445EBAA4C09D2E5C CRC64;
     MTLRLPKLIS DGMVLQRNKK VKIWGWAFPE EKVIVHFLDK SYSTIANSDG KWEVTLPELK
     AGGPYFMVIE ASQKSITINN ILIGDVWVCS GQSNMVLPME RVKDIYEEEI YSCDNPFIRQ
     FTVPDRYNFK GPQEDLPQGS WEELSKETIL RFSAVGYFFA KALFERYRVP IGLIKACVGG
     TPIEAWLSED ALKQFPENLK ILEQLRVDGY IESIKKKEES EISAWYENLN KNDKGMKLAW
     FDPDYDDSDW HTVNLPASWK EMGLDSLKGV VWFRKKVNVP AFMAGKPAKL YMGTIVDSDH
     TYVNGTLVGS ISYRYPPRKY EIPANLLKPG ENVIAIRVIS NDGNGEFVKG KPYKLFTKDY
     QISLEGEWKC KVGAEAPKPL PPMTFFEYKP AGLFNGMIAP LLKFAIKGVI WYQGESNTDN
     PKGYHEKFSA LITDWRQKWG QGDFPFLYVQ LANFMEAKSQ QSESKWAQLR EEQRKTLSVP
     NTGMAIAIDL GEWNDLHPSN KKDVGERLAL LARKIAYGEK DIVASGPLYK SMKIEGNKVI
     IEFSEVGSGL VAKGGGELKH FAIAGSDKKF VWAKAIIEGD KVVVWNDSIS NPAYVRYAWA
     DNPEGANLYN KEGLPASPFT TEEEV
//