ID G2T421_ROSHA Unreviewed; 225 AA.
AC G2T421;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=GntR domain protein {ECO:0000313|EMBL:AEN97466.1};
GN OrderedLocusNames=RHOM_11790 {ECO:0000313|EMBL:AEN97466.1};
OS Roseburia hominis (strain DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=585394 {ECO:0000313|EMBL:AEN97466.1, ECO:0000313|Proteomes:UP000008178};
RN [1] {ECO:0000313|EMBL:AEN97466.1, ECO:0000313|Proteomes:UP000008178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183
RC {ECO:0000313|Proteomes:UP000008178};
RX PubMed=26543119; DOI=10.1128/genomeA.01286-15;
RA Travis A.J., Kelly D., Flint H.J., Aminov R.I.;
RT "Complete genome sequence of the human gut symbiont Roseburia hominis.";
RL Genome Announc. 3:E0128615-E0128615(2015).
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DR EMBL; CP003040; AEN97466.1; -; Genomic_DNA.
DR RefSeq; WP_014080477.1; NC_015977.1.
DR AlphaFoldDB; G2T421; -.
DR STRING; 585394.RHOM_11790; -.
DR GeneID; 77459936; -.
DR KEGG; rho:RHOM_11790; -.
DR eggNOG; COG1802; Bacteria.
DR HOGENOM; CLU_017584_5_1_9; -.
DR OrthoDB; 9781630at2; -.
DR BioCyc; RHOM585394:G1H02-2353-MONOMER; -.
DR Proteomes; UP000008178; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RSPR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008178};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..80
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 225 AA; 26047 MW; 4FC5468E8E3226D3 CRC64;
MTEDLTLNMN AYLPLRDVVF NTLREAILKG ELKPGERLME LQLAAKLGVS RTPIREAIRM
LEQEGLAVTI PRKGAEVARM TEKDMEDVLQ IRDALDELAA SIACEQISEE ELAELRHTMH
EFEESTKTGD VKRIAEADVR FHDIIYHATR NVKLENMLNN LREQMYRYRV EYLKDEKNFP
ILIREHSQIV EGLTAKDKTM LTAAMHKHVM NQATAVKEMI REQEK
//
